Wayfinding Intervention and Long-Term Memory

Description

Therapeutic treatment is yet available for declining memory, which is an impairment affecting the quality of life for many older adults and patients with cognitive impairment. Cognitive training with an immersive video game promises to drive hippocampal-cortical plasticity and associated gains that can restore memory capability or provide therapeutic treatment for memory deficits.

Conditions

Long-Term Memory Decline, Mild Cognitive Impairment

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Study Overview

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Study Details

Study overview

Therapeutic treatment is yet available for declining memory, which is an impairment affecting the quality of life for many older adults and patients with cognitive impairment. Cognitive training with an immersive video game promises to drive hippocampal-cortical plasticity and associated gains that can restore memory capability or provide therapeutic treatment for memory deficits.

Virtual Reality Interventions to Stimulate Capabilities for Learning and Retrieval of High-Fidelity Memory

Wayfinding Intervention and Long-Term Memory

Condition
Long-Term Memory Decline
Intervention / Treatment

-

Contacts and Locations

San Francisco

UCSF Mission Bay, San Francisco, California, United States, 94158

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * fluent speakers of English
  • * completed 12 or more years of education
  • * normal or corrected-to-normal vision
  • * dexterity to comfortably operate the scanner-compatible response box
  • * freedom from physical and neurological conditions contra-indicated for fMRI
  • * must confirm physical stamina and comfort for semi-weekly brisk 30-minute walks on level ground
  • * use of psychotropic medications
  • * history of concussions or dizziness, vestibular or balance problems
  • * significant discomfort with virtual reality experiences

Ages Eligible for Study

60 Years to 85 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of California, San Francisco,

Peter E Wais, PhD, PRINCIPAL_INVESTIGATOR, Neuroscape, Department of Neurology

Study Record Dates

2026-01-31