RECRUITING

Wayfinding Intervention and Long-Term Memory

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Therapeutic treatment is yet available for declining memory, which is an impairment affecting the quality of life for many older adults and patients with cognitive impairment. Cognitive training with an immersive video game promises to drive hippocampal-cortical plasticity and associated gains that can restore memory capability or provide therapeutic treatment for memory deficits.

Official Title

Virtual Reality Interventions to Stimulate Capabilities for Learning and Retrieval of High-Fidelity Memory

Quick Facts

Study Start:2024-01-01
Study Completion:2026-01-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05625425

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:60 Years to 85 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * fluent speakers of English
  2. * completed 12 or more years of education
  3. * normal or corrected-to-normal vision
  4. * dexterity to comfortably operate the scanner-compatible response box
  5. * freedom from physical and neurological conditions contra-indicated for fMRI
  6. * must confirm physical stamina and comfort for semi-weekly brisk 30-minute walks on level ground
  1. * use of psychotropic medications
  2. * history of concussions or dizziness, vestibular or balance problems
  3. * significant discomfort with virtual reality experiences

Contacts and Locations

Study Contact

Melissa Arioli
CONTACT
415-502-7321
melissa.arioli@ucsf.edu

Principal Investigator

Peter E Wais, PhD
PRINCIPAL_INVESTIGATOR
Neuroscape, Department of Neurology

Study Locations (Sites)

UCSF Mission Bay
San Francisco, California, 94158
United States

Collaborators and Investigators

Sponsor: University of California, San Francisco

  • Peter E Wais, PhD, PRINCIPAL_INVESTIGATOR, Neuroscape, Department of Neurology

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-01-01
Study Completion Date2026-01-31

Study Record Updates

Study Start Date2024-01-01
Study Completion Date2026-01-31

Terms related to this study

Keywords Provided by Researchers

  • amnestic MCI without dementia
  • cognitive training
  • cognitive aging

Additional Relevant MeSH Terms

  • Long-Term Memory Decline
  • Mild Cognitive Impairment