RECRUITING

Human Papillomavirus (HPV) Vaccination vs. Placebo for the Treatment of Refractory Cutaneous Warts

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This double-blinded clinical trial randomly assigns participants with refractory cutaneous warts to receive either treatment with the human papillomavirus (HPV) vaccine or a placebo to assess the efficacy of HPV vaccination for the treatment of refractory cutaneous warts.

Official Title

Human Papillomavirus (HPV) Vaccination for the Treatment of Refractory Cutaneous Warts: A Randomized, Placebo-Controlled, Double-Blinded Trial

Quick Facts

Study Start:2024-03-25
Study Completion:2026-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05625633

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Must be able to understand and provide written informed consent
  2. 2. Age 18 or older
  3. 3. Clinical diagnosis of cutaneous warts
  4. 4. Must have received prior treatment for cutaneous warts (such as curettage, cryotherapy, salicylic acid, intralesional Candida antigen injection, etc.)
  1. 1. Untreated cutaneous warts
  2. 2. Anogenital warts
  3. 3. Oral warts
  4. 4. Treatment for cutaneous warts in the past 4 weeks
  5. 5. Active acute illness
  6. 6. Immunosuppression
  7. 7. Known hypersensitivity to HPV vaccination
  8. 8. Subjects may not receive any other investigational treatment
  9. 9. Pregnancy or planned pregnancy during the study period

Contacts and Locations

Study Contact

Lowell Nicholson, MD
CONTACT
801-581-2121
lowell.nicholson@hsc.utah.edu
Jamie Rhoads, MD
CONTACT
801-581-2121
jamie.rhoads@hsc.utah.edu

Principal Investigator

Lowell Nicholson, MD
PRINCIPAL_INVESTIGATOR
University of Utah Health Care System

Study Locations (Sites)

University of Utah Midvalley Health Center
Salt Lake City, Utah, 84107
United States
VA Salt Lake City Health Care System
Salt Lake City, Utah, 84148
United States

Collaborators and Investigators

Sponsor: Western Institute for Veterans Research

  • Lowell Nicholson, MD, PRINCIPAL_INVESTIGATOR, University of Utah Health Care System

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-03-25
Study Completion Date2026-12

Study Record Updates

Study Start Date2024-03-25
Study Completion Date2026-12

Terms related to this study

Keywords Provided by Researchers

  • Refractory cutaneous warts
  • Human Papillomavirus (HPV) Vaccination
  • HPV vaccine

Additional Relevant MeSH Terms

  • Warts