ACTIVE_NOT_RECRUITING

Promoting Cognitive Resilience and Reducing Frailty in Older Veterans With Bright Light Therapy

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Frailty is a multifactorial syndrome characterized by vulnerability to stressors that is intricately linked to cognitive impairment and mortality risk. Bright light therapy (BLT) reduces circadian disturbances by resynchronizing the hypothalamic biological clock via specific wavelengths of light. Human trials have demonstrated that BLT improves sleep quality and cognitive function in older adults. However, BLT has not been examined for use in older Veteran populations, particularly the impact on frailty. This randomized trial will assess the feasibility of employing BLT to study impacts on frailty, cognition, and sleep in older Veterans. Findings from this pilot will establish the power and effect size necessary for larger trials to support the use of BLT as readily available home-based treatment to improve healthspan of Veterans.

Official Title

Promoting Cognitive Resilience and Reducing Frailty in Older Veterans With Bright Light Therapy

Quick Facts

Study Start:2024-01-29
Study Completion:2025-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:ACTIVE_NOT_RECRUITING

Study ID

NCT05631236

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:60 Years to 85 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Participants studied in this project will include 30 men and 5 women of any race who are community dwellers
  2. * The investigators seek to recruit relatively healthy individuals that may or may not exhibit early-stage co-morbidities
  1. * The investigators will exclude individuals without sleep disturbances (PSQI \>5)
  2. * Are morbidly obese (BMI \> 40)
  3. * Exhibit severe or advanced co-morbidities, or have cognitive impairment

Contacts and Locations

Principal Investigator

Bruce R. Troen, MD
PRINCIPAL_INVESTIGATOR
Kansas City VA Medical Center, Kansas City, MO

Study Locations (Sites)

Kansas City VA Medical Center, Kansas City, MO
Kansas City, Missouri, 64128-2226
United States
Kansas City VA Medical Center, Kansas City, MO
Kansas City, Missouri, 64128
United States

Collaborators and Investigators

Sponsor: VA Office of Research and Development

  • Bruce R. Troen, MD, PRINCIPAL_INVESTIGATOR, Kansas City VA Medical Center, Kansas City, MO

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-01-29
Study Completion Date2025-12-31

Study Record Updates

Study Start Date2024-01-29
Study Completion Date2025-12-31

Terms related to this study

Keywords Provided by Researchers

  • sleep
  • aging
  • veteran
  • cognition
  • dementia
  • functional capacity
  • frailty

Additional Relevant MeSH Terms

  • Veteran Aged 65 and Older