Miniscrew Stability and Peri-implant Inflammation When Precoated K21 vs Ethanol Control

Description

To determine if coating miniscrews with K21 would increase the success rate of orthodontic miniscrews by reducing adjacent tissue inflammation.

Conditions

Inflammation Caused by the Placement of a Temporary Anchorage Device

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Study Overview

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Study Details

Study overview

To determine if coating miniscrews with K21 would increase the success rate of orthodontic miniscrews by reducing adjacent tissue inflammation.

A Comparison of Miniscrew Stability and Peri-implant Inflammation When Precoated With Antimicrobial Quaternary Ammonium Compound K21 vs Ethanol Control in Orthodontic Patients: a Triple-blind, Split-mouth, Randomized Controlled Clinical Trial

Miniscrew Stability and Peri-implant Inflammation When Precoated K21 vs Ethanol Control

Condition
Inflammation Caused by the Placement of a Temporary Anchorage Device
Intervention / Treatment

-

Contacts and Locations

Aurora

University of Colorado School of Dental Medicine, Aurora, Colorado, United States, 80045

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Good general health, with no significant medical findings
  • 2. Requiring at least two miniscrews in their treatment plans (i.e., most participants will have two miniscrews, but some may receive four or six as indicated by their individual treatment plan)
  • 3. Miniscrew pairs indicated with comparable anatomical positions and comparable mechanics (direct vs. indirect anchorage).
  • 1. Recent or ongoing use of antiresorptive pharmacological agents contraindicating the use of orthodontic miniscrews
  • 2. Less than 12 years of age
  • 3. Heavy tobacco use (\>10 cigarettes/day)
  • 4. Peri-implant tissues must be observable at follow-up appointments
  • 5. Being unable or unwilling to consent to the study

Ages Eligible for Study

12 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Colorado, Denver,

Study Record Dates

2025-06