RECRUITING

Impact of Dietary Fiber Supplementation on Colonic Mucosal Microbiome

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This clinical trial tests whether daily fiber supplementation will change the mucosal microbiome of the colon. The microbiome are microorganisms that live in the human gut. They serve a vital role in maintaining health. Certain microbial strains are associated with the growth of colon polyps, which eventually could go on to form colon cancer. Giving dietary fiber supplements may help prevent precancerous polyps from ever developing.

Official Title

Changes in Colonic Microbiome With Fiber Supplementation

Quick Facts

Study Start:2023-04-01
Study Completion:2024-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05643859

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Age \>= 18 years
  2. * Ability to understand and the willingness to sign a written informed consent document
  3. * Patients who present with a chief complaint of a benign anorectal pathology including hemorrhoids, anal fissures, and anal fistulas without underlying conditions such as cancer or Crohn's disease or are undergoing a standard of care colonoscopy procedure
  1. * Patients with an active malignancy, Crohn's disease, ulcerative colitis, and immunosuppressed patients.
  2. * Patients with hereditary colon cancer syndrome including Lynch syndrome or Familial Adenomatous Polyposis (FAP)
  3. * Patients with a prior history of total or partial colon resection.
  4. * Colorectal pathology such as polyps or cancer

Contacts and Locations

Study Contact

Shahrose Rahman, M.D.
CONTACT
503-494-8652
rahmasha@ohsu.edu
Amber O'Connor
CONTACT
oconnoam@ohsu.edu

Principal Investigator

Vassiliki L Tsikitis, M.D.
PRINCIPAL_INVESTIGATOR
OHSU Knight Cancer Institute

Study Locations (Sites)

OHSU Knight Cancer Institute
Portland, Oregon, 97239
United States

Collaborators and Investigators

Sponsor: OHSU Knight Cancer Institute

  • Vassiliki L Tsikitis, M.D., PRINCIPAL_INVESTIGATOR, OHSU Knight Cancer Institute

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-04-01
Study Completion Date2024-12-31

Study Record Updates

Study Start Date2023-04-01
Study Completion Date2024-12-31

Terms related to this study

Additional Relevant MeSH Terms

  • Benign Colorectal Neoplasm
  • Non-Neoplastic Anal Disorder