A Study of YL202 in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer and Breast Cancer

Description

This is a phase 1, multicenter, open-label, first-in-human study of YL202 conducted in the United States and China. The study will evaluate the safety and tolerability of YL202 in patients with locally advanced or metastatic epidermal growth factor receptor (EGFR)-mutated NSCLC or hormone receptor (HR)-positive and HER2-negative BC, which have been heavily treated by standard treatment.

Conditions

Non Small Cell Lung Cancer, Breast Cancer

Study Overview

Study Details

Study overview

This is a phase 1, multicenter, open-label, first-in-human study of YL202 conducted in the United States and China. The study will evaluate the safety and tolerability of YL202 in patients with locally advanced or metastatic epidermal growth factor receptor (EGFR)-mutated NSCLC or hormone receptor (HR)-positive and HER2-negative BC, which have been heavily treated by standard treatment.

A Phase 1, Multicenter, Open-label, First-in-human Study of YL202 in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer and Breast Cancer

A Study of YL202 in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer and Breast Cancer

Condition
Non Small Cell Lung Cancer
Intervention / Treatment

-

Contacts and Locations

Plantation

BRCR Global, Plantation, Florida, United States, 33322

Detroit

Karmanos Cancer Institute, Detroit, Michigan, United States, 48201

Houston

The University of Texas MD Anderson Cancer Center, Houston, Texas, United States, 77030

Irving

Next Oncology-Dallas, Irving, Texas, United States, 75039

Tyler

UT health east Texas HOPE Cancer Center, Tyler, Texas, United States, 75701

Fairfax

Next Oncology-Virginia, Fairfax, Virginia, United States, 22031

Spokane Valley

Summit Cancer Center, Spokane Valley, Washington, United States, 99216

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

    Ages Eligible for Study

    18 Years to

    Sexes Eligible for Study

    ALL

    Accepts Healthy Volunteers

    No

    Collaborators and Investigators

    MediLink Therapeutics (Suzhou) Co., Ltd.,

    Study Record Dates

    2026-12