RECRUITING

Optimizing Evidence-based HIV Prevention Targeting People Who Inject Drugs on PrEP

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The investigators will conduct an optimization trial among N=256 PWID newly started on medication for opioid use disorder and Pre-Exposure Prophylaxis (PrEP) to assess the performance of four intervention components (Attention, Executive Functioning, Memory, and Information Processing) aimed at enhancing the ability of PWID on MOUD to process and utilize HIV prevention content, leading to improvements in HIV prevention information, motivation, behavioral skills, and behaviors (IMB).

Official Title

Optimizing Evidence-based HIV Prevention Targeting People Who Inject Drugs on PrEP

Quick Facts

Study Start:2023-03-01
Study Completion:2027-01-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05669534

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * being 18 years or older
  2. * meeting DSM-V criteria for opioid dependence and being newly prescribed and adherent to Medication for Opioid Use Disorder (e.g., methadone, buprenorphine) at the APT Foundation, Inc.
  3. * showing mild cognitive impairment based on the Montreal Cognitive Assessment (MoCA) screening
  4. * having initiated Pre-Exposure Prophylaxis (PrEP) within the past week
  5. * confirming HIV-negative status through proof of PrEP prescription
  6. * reporting unsafe injection drug use practices or unprotected sex within the past 3 months
  7. * having a cell phone
  8. * being able to read and understand in English
  1. * unable to provide consent
  2. * actively suicidal
  3. * actively homicidal
  4. * actively psychotic
  5. * display MoCA scores suggestive of dementia

Contacts and Locations

Study Contact

Brian Sibilio, BS
CONTACT
2037814690
brian.sibilio@uconn.edu
Tanya Adler, MS
CONTACT
2037814690
tanya.adler@uconn.edu

Principal Investigator

Michael Copenhaver, PhD
PRINCIPAL_INVESTIGATOR
University of Connecticut

Study Locations (Sites)

APT Foundation
New Haven, Connecticut, 06519
United States

Collaborators and Investigators

Sponsor: University of Connecticut

  • Michael Copenhaver, PhD, PRINCIPAL_INVESTIGATOR, University of Connecticut

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-03-01
Study Completion Date2027-01-01

Study Record Updates

Study Start Date2023-03-01
Study Completion Date2027-01-01

Terms related to this study

Keywords Provided by Researchers

  • people who inject drugs
  • HIV
  • cognitive dysfunction
  • pre-exposure prophylaxis
  • multiphase optimization strategy
  • medication for opioid use disorder
  • opioid use disorder

Additional Relevant MeSH Terms

  • Hiv
  • Opioid Use Disorder