Optimizing Evidence-based HIV Prevention Targeting People Who Inject Drugs on PrEP

Description

The investigators will conduct an optimization trial among N=256 PWID newly started on medication for opioid use disorder and Pre-Exposure Prophylaxis (PrEP) to assess the performance of four intervention components (Attention, Executive Functioning, Memory, and Information Processing) aimed at enhancing the ability of PWID on MOUD to process and utilize HIV prevention content, leading to improvements in HIV prevention information, motivation, behavioral skills, and behaviors (IMB).

Conditions

Hiv, Opioid Use Disorder

Study Overview

Study Details

Study overview

The investigators will conduct an optimization trial among N=256 PWID newly started on medication for opioid use disorder and Pre-Exposure Prophylaxis (PrEP) to assess the performance of four intervention components (Attention, Executive Functioning, Memory, and Information Processing) aimed at enhancing the ability of PWID on MOUD to process and utilize HIV prevention content, leading to improvements in HIV prevention information, motivation, behavioral skills, and behaviors (IMB).

Optimizing Evidence-based HIV Prevention Targeting People Who Inject Drugs on PrEP

Optimizing Evidence-based HIV Prevention Targeting People Who Inject Drugs on PrEP

Condition
Hiv
Intervention / Treatment

-

Contacts and Locations

New Haven

APT Foundation, New Haven, Connecticut, United States, 06519

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * being 18 years or older
  • * meeting DSM-V criteria for opioid dependence and being newly prescribed and adherent to Medication for Opioid Use Disorder (e.g., methadone, buprenorphine) at the APT Foundation, Inc.
  • * showing mild cognitive impairment based on the Montreal Cognitive Assessment (MoCA) screening
  • * having initiated Pre-Exposure Prophylaxis (PrEP) within the past week
  • * confirming HIV-negative status through proof of PrEP prescription
  • * reporting unsafe injection drug use practices or unprotected sex within the past 3 months
  • * having a cell phone
  • * being able to read and understand in English
  • * unable to provide consent
  • * actively suicidal
  • * actively homicidal
  • * actively psychotic
  • * display MoCA scores suggestive of dementia

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Connecticut,

Michael Copenhaver, PhD, PRINCIPAL_INVESTIGATOR, University of Connecticut

Study Record Dates

2027-01-01