Impact of Gut Microbiome on Metabolic and Bowel Function During the First Year After Spinal Cord Injury

Description

The Investigators will recruit 35 participants with acute SCI (within 6 weeks of injury) Fasting blood collection and bowel function survey will be conducted 3 times: at baseline \[within 6 weeks of injury\], 6, and 12 months after SCI. Stool will be collected for gut microbiome analysis 3 times.

Conditions

Spinal Cord Injuries, Gut Microbiome

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Study Overview

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Study Details

Study overview

The Investigators will recruit 35 participants with acute SCI (within 6 weeks of injury) Fasting blood collection and bowel function survey will be conducted 3 times: at baseline \[within 6 weeks of injury\], 6, and 12 months after SCI. Stool will be collected for gut microbiome analysis 3 times.

Impact of Gut Microbiome on Metabolic and Bowel Function During the First Year After Spinal Cord Injury

Impact of Gut Microbiome on Metabolic and Bowel Function During the First Year After Spinal Cord Injury

Condition
Spinal Cord Injuries
Intervention / Treatment

-

Contacts and Locations

Birmingham

The University of Alabama at Birmingahm, Birmingham, Alabama, United States, 35294

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. 18-85 years of age
  • 2. diagnosis of traumatic SCI at the cervical to lumbar level (C3-L2)
  • 3. classification of A, B, C (motor complete, incomplete).
  • 1. Women who are pregnant prior to consent
  • 2. neurological impairment other than SCI
  • 3. self-reported history of Crohn's disease or diverticulitis
  • 4. irritable bowel syndrome
  • 5. gastric blockage/obstruction or swallowing disorder
  • 6. prior GI surgery
  • 7. intrathecal pump
  • 8. concurrent usage of functional electrical stimulation for bowel management (e.g., constipation).
  • 9. able to ambulate

Ages Eligible for Study

18 Years to 85 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Alabama at Birmingham,

Jereme Wilroy, PhD, PRINCIPAL_INVESTIGATOR, University of Alabama at Birmingham

Study Record Dates

2027-02-28