Prospective Evaluation of Intrathecal Targeted Drug Delivery for Cancer Associated Pain

Description

This Registry study will prospectively evaluate the differences in treatment outcomes in terms of pain intensity, pain interference, concomitant medication use, health-related quality of life, opioid adverse effects, and healthcare utilization between targeted drug delivery and conservative medication management only groups.

Conditions

Cancer Pain, Chronic Pain, Cancer Associated Pain, Neuropathic Pain

Study Overview

Study Details

Study overview

This Registry study will prospectively evaluate the differences in treatment outcomes in terms of pain intensity, pain interference, concomitant medication use, health-related quality of life, opioid adverse effects, and healthcare utilization between targeted drug delivery and conservative medication management only groups.

Intrathecal Targeted Drug Delivery for Cancer Associated Pain

Prospective Evaluation of Intrathecal Targeted Drug Delivery for Cancer Associated Pain

Condition
Cancer Pain
Intervention / Treatment

-

Contacts and Locations

Oshkosh

Advocate Aurora Health, Oshkosh, Wisconsin, United States, 54904

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Age of 21 and older
  • * Uncontrolled cancer-associated pain (pain score of \>5 on NRS) despite oral use of 60 mg/d morphine equivalent a week prior to screening
  • * Adverse side effects from long term opioid use defined as limiting or severely affecting patient's day to day function
  • * Life expectancy of \> 3 months
  • * Active infections
  • * Controlled pain without adverse side effects that are limiting day to day function
  • * Mechanical barriers
  • * Obstruction of Cerebrospinal Fluid (CSF)

Ages Eligible for Study

21 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Wake Forest University Health Sciences,

Mansoor M Aman, MD, PRINCIPAL_INVESTIGATOR, Wake Forest University Health Sciences

Study Record Dates

2025-12-06