Disparities in Emergency Contraceptive Metabolism Dictate Efficacy

Description

The purpose of this study is to learn more about why some people are at greater risk for oral emergency contraceptive failure while others are not. The investigators want to learn if genetic differences impact the risk of emergency contraception failure.

Conditions

Contraceptive Usage

Talk to us

Study Overview

On this page

Study Details

Study overview

The purpose of this study is to learn more about why some people are at greater risk for oral emergency contraceptive failure while others are not. The investigators want to learn if genetic differences impact the risk of emergency contraception failure.

Disparities in Emergency Contraceptive Metabolism Dictate Efficacy

Disparities in Emergency Contraceptive Metabolism Dictate Efficacy

Condition
Contraceptive Usage
Intervention / Treatment

-

Contacts and Locations

Portland

OHSU, Portland, Oregon, United States, 97239

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Generally healthy women
  • * Aged 18-40
  • * regular menses (every 21-35 days) experiencing ovulatory cycles proven by a single progesterone level of 3 ng/mL or greater during the luteal phase of the screening cycle.
  • * Pregnant, seeking pregnancy, or breastfeeding
  • * Known allergy to study medication
  • * Recent use of hormonal contraception
  • * Irregular periods (\<21 days or \>35 day cycles)
  • * Routine use of nonsteroidal anti-inflammatory drugs
  • * Metabolic disorders
  • * Smoking
  • * Any condition that would preclude the provision of informed consent
  • * Using drugs (within 2 weeks of study enrollment) known to interfere with the metabolism of UPA as well as drugs known to be CYP3A4 inducers, inhibitors, or CYP3A drug substrates

Ages Eligible for Study

18 Years to 40 Years

Sexes Eligible for Study

FEMALE

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Oregon Health and Science University,

ALISON EDELMAN, MD, PRINCIPAL_INVESTIGATOR, Oregon Health and Science University

Study Record Dates

2027-12-31