RECRUITING

PTSD Treatment for Veterans With Serious Mental Illness to Improve Functional Outcomes

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

PTSD is common among Veterans with serious mental illness (SMI). Co-occurring PTSD and SMI lead to poorer mental health and physical functioning than either diagnosis alone. Despite known high prevalence rates of PTSD in SMI populations as well as disparities in prevalence and treatment use for Black, Indigenous, and other people of color (BIPOC), little research has been done to: a) evaluate leading treatments for PTSD in individuals with SMI, and b) develop culturally responsive methods to integrate with PTSD treatments for SMI Veterans. This study aims to address research and clinical gaps by: a) testing the feasibility and acceptability of Written Exposure Therapy (WET), a VA evidence-based psychotherapy for PTSD in Veterans with SMI, and b) incorporating culturally responsive assessment methods. Results from this study will inform whether WET and culturally responsive assessment are feasible to implement, acceptable to Veterans with SMI, and worth examining in standard or optimized form in a larger clinical trial.

Official Title

PTSD Treatment for Veterans With Serious Mental Illness to Improve Functional Outcomes

Quick Facts

Study Start:2023-12-01
Study Completion:2028-03-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05674617

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * enrolled in outpatient mental health services within the VAMHCS (including general outpatient Mental Health Clinic (MHC), Psychosocial Rehabilitation and Recovery Centers (PRRCs), Mental Health Intensive Case Management (MHICM), and PTSD Clinical Teams (PCTs))
  2. * diagnosis of PTSD as confirmed by assessment with the Clinician-administered PTSD Scale for DSM-5 (CAPS-5) past month version
  3. * SMI diagnosis as defined by VHA Directive 1160 (i.e., psychotic spectrum or bipolar disorders) as confirmed by the medical record
  4. * regular telephone access
  1. * are engaging in moderate-to-severe substance use that would impact their ability to participate and/or would require a higher level of care
  2. * already engaged in trauma-focused EBP for PTSD (e.g., WET, CPT, PE, or EMDR) or completed an EBP for PTSD within the past 6 months

Contacts and Locations

Study Contact

Mary K Howell, PhD
CONTACT
(410) 605-7000
Mary.Howell@va.gov
Amy L Drapalski, PhD
CONTACT
(410) 637-1855
amy.drapalski@va.gov

Principal Investigator

Mary K Howell, PhD
PRINCIPAL_INVESTIGATOR
Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD

Study Locations (Sites)

Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD
Baltimore, Maryland, 21201
United States

Collaborators and Investigators

Sponsor: VA Office of Research and Development

  • Mary K Howell, PhD, PRINCIPAL_INVESTIGATOR, Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-12-01
Study Completion Date2028-03-31

Study Record Updates

Study Start Date2023-12-01
Study Completion Date2028-03-31

Terms related to this study

Keywords Provided by Researchers

  • Stress Disorders, Post-Traumatic
  • Mental Disorders
  • Culturally responsive assessment

Additional Relevant MeSH Terms

  • Stress Disorders, Post-Traumatic; Mental Disorders