Effectiveness of Relationship Education for Reducing HIV Incidence Among SGM

Description

The purpose of this study is to upgrade an existing relationship education and HIV prevention program. This program is designed for gay, bisexual, queer, and transgender and non-binary people who partner with cisgender men. This means the program is designed for gay, bisexual and queer men, including both cisgender and transgender men. It is also designed for transgender and non-binary people who partner with cisgender men, including both transfeminine and transmasculine people. The investigators aim to test the effectiveness of this updated program among couples and single people. Participants will complete online surveys and get tested for Chlamydia and Gonorrhea. Participants will be tested for urethral and rectal Chlamydia and Gonorrhea. Participants will also complete at-home point-of-care HIV testing, with confirmatory testing for preliminary positive results. They will also participate in our program on relationship education and HIV prevention. Study staff will follow up with participants for up to 2 years. All participants will be randomized into one of two different conditions: the all2GETHER program or no program. "Randomized" means that it is completely up to chance which condition participants will be put into. Participants have a 50% chance of being assigned to either condition, similar to a coin toss. Participants should expect that they will be in this research study for 2 years. Participation in this study will be done remotely - participants will never need to come into a research lab.

Conditions

Hiv, Chlamydia, Gonorrhea

Study Overview

Study Details

Study overview

The purpose of this study is to upgrade an existing relationship education and HIV prevention program. This program is designed for gay, bisexual, queer, and transgender and non-binary people who partner with cisgender men. This means the program is designed for gay, bisexual and queer men, including both cisgender and transgender men. It is also designed for transgender and non-binary people who partner with cisgender men, including both transfeminine and transmasculine people. The investigators aim to test the effectiveness of this updated program among couples and single people. Participants will complete online surveys and get tested for Chlamydia and Gonorrhea. Participants will be tested for urethral and rectal Chlamydia and Gonorrhea. Participants will also complete at-home point-of-care HIV testing, with confirmatory testing for preliminary positive results. They will also participate in our program on relationship education and HIV prevention. Study staff will follow up with participants for up to 2 years. All participants will be randomized into one of two different conditions: the all2GETHER program or no program. "Randomized" means that it is completely up to chance which condition participants will be put into. Participants have a 50% chance of being assigned to either condition, similar to a coin toss. Participants should expect that they will be in this research study for 2 years. Participation in this study will be done remotely - participants will never need to come into a research lab.

Effectiveness of Relationship Education for Reducing HIV Incidence in Men Who Have Sex With Men

Effectiveness of Relationship Education for Reducing HIV Incidence Among SGM

Condition
Hiv
Intervention / Treatment

-

Contacts and Locations

Chicago

Northwestern University, Chicago, Illinois, United States, 60611

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Cisgender men, transgender women and men, non-binary individuals
  • * Had condomless anal sex with 2 or more serodiscordant/unknown-status cisgender male partners in the last 6 months
  • * Aged 16-34 years
  • * Lab-test confirmed HIV-negative
  • * Read and speak English at 8th grade level or better
  • * Internet access
  • * Agree to audio recording of intervention sessions
  • * Provides address to receive HIV/STI test supplies
  • * For dyads, both partners may enroll if they meet the above criteria- partners who are aged 35+ and/or HIV-positive may enroll in a more limited capacity

Ages Eligible for Study

16 Years to 34 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Northwestern University,

Michael E Newcomb, Ph.D, PRINCIPAL_INVESTIGATOR, Northwestern University

Kathryn Macapagal, Ph.D, PRINCIPAL_INVESTIGATOR, Northwestern University

Elissa Sarno, Ph.D, STUDY_DIRECTOR, Northwestern University

Brian Mustanski, Ph.D, PRINCIPAL_INVESTIGATOR, Northwestern University

Dennis Li, Ph.D, PRINCIPAL_INVESTIGATOR, Northwestern University

Jody Ciolino, Ph.D, PRINCIPAL_INVESTIGATOR, Northwestern University

Jim Carey, MPH, STUDY_DIRECTOR, Northwestern University

Study Record Dates

2026-03-31