RECRUITING

PyloPlus Urea Breath Test System Post Therapy Efficacy Confirmation Study

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This is a multi-center, non-randomized, open label study. Subjects will be enrolled if they are deemed eligible given the inclusion criteria. Subjects who meet all inclusion criteria and none of the exclusion criteria will be entered into the study. Subjects will be exposed to non-radioactive 13C-Urea with citric acid, and may submit a stool sample or undergo endoscopy for Rapid Urease Test and Histology samples. Center(s) will house a PyloPlus UBT Analyzer to document results. PyloPlus Analyzer results shall remain blinded to the investigator and treating physician. No patient management decisions should be made based on the investigational PyloPlus UBT System. Treating physician will either prescribe a H. pylori Stool Antigen Test through P4 Diagnostics, along with another Urea Breath Test using Breath ID, or patient will undergo Endoscopy to provide a composite reference method consisting of Rapid Urease Test and Histology. These will act as the comparators to the PyloPlus Urea Breath Test System.

Official Title

PyloPlus Urea Breath Test System Post Therapy Efficacy Confirmation Study

Quick Facts

Study Start:2022-12-21
Study Completion:2023-06
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05681689

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Male or Female at least 18 years of age
  2. * Patients who have been diagnosed with H. pylori and have been treated within the past 6 months
  3. * Naive to H. pylori treatment in the past 4 weeks (including PPIs)
  1. * Pregnant and/or lactating women.
  2. * Presence of a condition or abnormality that in the opinion of the Investigator would compromise the safety of the patient or the quality of the data.
  3. * Participation in other interventional trials.
  4. * Allergy to test substrates.
  5. * Antibiotics taken within 4 weeks of the testing.
  6. * Study subjects shall not consume the following items at least 1 hour prior to the PPUBT test: Mouthwash, Chewing Gum, Carbonated Beverages, Cigarette Smoke, Acetone (to simulate the effect of ketone production that may result from some diets), Alcohol, Food

Contacts and Locations

Study Contact

Clinical Trial Manager
CONTACT
877-855-4100
info@gulfcoastscientific.com

Study Locations (Sites)

Dolphin Medical Research
Doral, Florida, 33172
United States
Hudson County Clinical Trials Research Center
Union City, New Jersey, 07087
United States

Collaborators and Investigators

Sponsor: ARJ Medical, Inc.

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-12-21
Study Completion Date2023-06

Study Record Updates

Study Start Date2022-12-21
Study Completion Date2023-06

Terms related to this study

Additional Relevant MeSH Terms

  • Helicobacter Pylori Infection
  • Post-Treatment
  • Efficacy