ACTIVE_NOT_RECRUITING

Psychosocial Mobile App for Chronic Graft-Versus-Host Disease

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this research study is to see whether a psychosocial mobile app called Horizons is effective at improving quality of life, symptom burden, psychological distress, and coping in patients living with chronic graft-versus host disease (GVHD)

Official Title

Randomized Controlled Trial of a Psychosocial Mobile Application (App) to Promote Coping for Patients With Chronic Graft-Versus-Host Disease (GVHD)

Quick Facts

Study Start:2023-01-23
Study Completion:2026-06-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:ACTIVE_NOT_RECRUITING

Study ID

NCT05690971

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Adult patients (≥18 years) who underwent allogeneic hematopoietic stem cell transplant (HCT).
  2. * Have moderate to severe chronic GVHD based on their oncology clinician assessment as documented in the Electronic Health Record.
  3. * Ability to comprehend and speak English as the HORIZONs app is only available in English.
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Principal Investigator

Areej El-Jawahri, MD
PRINCIPAL_INVESTIGATOR
Massachusetts General Hospital

Study Locations (Sites)

Massachusetts General Hospital Cancer Center
Boston, Massachusetts, 02215
United States

Collaborators and Investigators

Sponsor: Massachusetts General Hospital

  • Areej El-Jawahri, MD, PRINCIPAL_INVESTIGATOR, Massachusetts General Hospital

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-01-23
Study Completion Date2026-06-01

Study Record Updates

Study Start Date2023-01-23
Study Completion Date2026-06-01

Terms related to this study

Keywords Provided by Researchers

  • Chronic Graft-Versus-Host Disease
  • Allogeneic Stem Cell Transplant

Additional Relevant MeSH Terms

  • Chronic Graft-Versus-Host Disease
  • Allogeneic Stem Cell Transplant