Discovering Novel Cancer Treatment Options Using a Comprehensive NGS-based Molecular Testing Panel in the Community Setting ("DINOSAur")

Description

To prospectively identify cancer patients whose tumors express specific molecular markers targeted by therapeutic agents from a comprehensive molecular test, for the purpose of selecting the most clinically appropriate treatment in a pragmatic two arm trial.

Conditions

Stage III Solid Tumors, Stage IV Solid Tumors

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Study Overview

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Study Details

Study overview

To prospectively identify cancer patients whose tumors express specific molecular markers targeted by therapeutic agents from a comprehensive molecular test, for the purpose of selecting the most clinically appropriate treatment in a pragmatic two arm trial.

Discovering Novel Cancer Treatment Options Using a Comprehensive NGS-based Molecular Testing Panel in the Community Setting ("DINOSAur")

Discovering Novel Cancer Treatment Options Using a Comprehensive NGS-based Molecular Testing Panel in the Community Setting ("DINOSAur")

Condition
Stage III Solid Tumors
Intervention / Treatment

-

Contacts and Locations

Glendale

Adventist Health Glendale, Glendale, California, United States, 91206

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Patients who have given informed consent in accordance with the methods and procedures of this study
  • * Diagnosis of cancer (stage 3 and stage 4; solid tumors only) requiring medical care
  • * Patients who have not received treatment related to his/her cancer
  • * Patients who are willing to sign a release of medical records to the research team
  • * Male and female patients ≥18 years of age
  • * Patients under oncology care of a participating site
  • * Sufficient clinical status for collection of biospecimen samples within usual care
  • * Patients who have insurance coverage for CMT
  • * Patients considered minors in the jurisdiction where the protocol is conducted.
  • * Patients who are prisoners and pregnant women.
  • * Patients who cannot provide consent and did not sign a power of attorney.

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Glendale Adventist Medical Center d/b/a Adventist Health Glendale,

Study Record Dates

2025-11-01