Sperm Preparation Prior to Intrauterine Insemination Study

Description

This is a randomized controlled trial comparing density gradient centrifugation and microfluidic sperm sorting in patients undergoing intrauterine insemination to evaluate cumulative pregnancy outcomes.

Conditions

Infertility, Infertility Secondary, Infertility Unexplained, Anovulation, Fertility Disorders, Reproductive Issues

Study Overview

Study Details

Study overview

This is a randomized controlled trial comparing density gradient centrifugation and microfluidic sperm sorting in patients undergoing intrauterine insemination to evaluate cumulative pregnancy outcomes.

The Sperm Preparation Prior to Intrauterine Insemination Study (PIoUS)

Sperm Preparation Prior to Intrauterine Insemination Study

Condition
Infertility
Intervention / Treatment

-

Contacts and Locations

San Francisco

UCSF Center for Reproductive Health, San Francisco, California, United States, 94158

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Patients undergoing intrauterine insemination
  • * Patient assigned female at birth with age \<41
  • * Any significant disease or psychiatric disorder that would interfere with the consenting process
  • * Prior intrauterine insemination
  • * Use of frozen donor sperm
  • * Non-English speaker

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of California, San Francisco,

Mitchell Rosen, MD, PRINCIPAL_INVESTIGATOR, University of California, San Francisco

Study Record Dates

2025-12-31