Discovering Novel Cancer Treatment Options Using a Comprehensive NGS-based Liquid Molecular Testing Panel in the Community Setting ("DINOSAur II")

Description

To prospectively identify cancer patients whose tumors express specific molecular markers targeted by therapeutic agents from a comprehensive l i q u i d molecular test, for the purpose of selecting the most clinically appropriate treatment in a pragmatic two arm trial.

Conditions

Stage III Solid Tumors, Stage IV Solid Tumors

Study Overview

Study Details

Study overview

To prospectively identify cancer patients whose tumors express specific molecular markers targeted by therapeutic agents from a comprehensive l i q u i d molecular test, for the purpose of selecting the most clinically appropriate treatment in a pragmatic two arm trial.

Discovering Novel Cancer Treatment Options Using a Comprehensive NGS-based Liquid Molecular Testing Panel in the Community Setting. ("DINOSAur II")

Discovering Novel Cancer Treatment Options Using a Comprehensive NGS-based Liquid Molecular Testing Panel in the Community Setting ("DINOSAur II")

Condition
Stage III Solid Tumors
Intervention / Treatment

-

Contacts and Locations

Glendale

Adventist Health Glendale, Glendale, California, United States, 91206

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Patients who have given informed consent in accordance with the methods and procedures of this study
  • * Diagnosis of cancer (stage 3 and stage 4; solid tumors only) requiring medical care
  • * Patients who have not received treatment related to his/her cancer
  • * Patients who are willing to sign a release of medical records to the research team
  • * Male and female patients ≥18 years of age
  • * Patients under oncology care
  • * Sufficient clinical status for collection of blood sample within usual care
  • * Patients considered minors in the jurisdiction where the protocol is conducted
  • * Patients who are prisoners and pregnant women
  • * Patients who cannot provide consent and did not sign a power of attorney

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Glendale Adventist Medical Center d/b/a Adventist Health Glendale,

Mihran H Shirinian, MD, PRINCIPAL_INVESTIGATOR, Glendale Adventist Medical Center dba Adventist Health Glendale

Study Record Dates

2025-01-01