Retrospective Review of Esophageal Cancer at MSKCC

Description

Residual tumor at the proximal or distal margin after esophagectomy is a known prognostic factor for poor survival outcomes in patients with esophageal cancer; however, the significance of the circumferential resection margin (CRM) remains controversial. In this study, the investigators sought to evaluate the prognostic significance of the CRM in patients with esophageal cancer undergoing resection.

Conditions

Esophageal Cancer, Esophagus Cancer

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Study Overview

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Study Details

Study overview

Residual tumor at the proximal or distal margin after esophagectomy is a known prognostic factor for poor survival outcomes in patients with esophageal cancer; however, the significance of the circumferential resection margin (CRM) remains controversial. In this study, the investigators sought to evaluate the prognostic significance of the CRM in patients with esophageal cancer undergoing resection.

Retrospective Review of Esophageal Cancer at MSKCC

Retrospective Review of Esophageal Cancer at MSKCC

Condition
Esophageal Cancer
Intervention / Treatment

-

Contacts and Locations

New York

Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York, New York, United States, 10065

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Histologically confirmed esophageal adenocarcinoma (EAC) or esophageal squamous cell carcinoma (ESCC) undergoing esophagectomy
  • * Pathologic staged T3 tumors (pT3)
  • * Pathologic staged T0-2 (pT0-2) or T4 tumors (pT4)
  • * Patients with histologic types other than EAC or ESCC, dysplasia or carcinoma in situ without tumor invasion,
  • * Patients undergoing salvage esophagectomy
  • * Evidence of distant metastatic disease
  • * Patients with a positive proximal or distal margin

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Memorial Sloan Kettering Cancer Center,

Daniela Molena, MD, PRINCIPAL_INVESTIGATOR, Memorial Sloan Kettering Cancer Center

Study Record Dates

2025-02