RECRUITING

Striated Esophageal Motor Function Modulation in Health and Disease

Conditions

Quick Navigation

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The investigators hypothesize that striated esophagus deglutitive motor function is modulated by pharyngeal phase swallowing biomechanics.

Official Title

Characterization of the Striated Esophagus (St.Eso) Deglutitive Motor Function and Its Modulation by Pharyngeal Phase Swallow Biomechanics

Quick Facts

Study Start:2022-09-13

Study Completion:2026-04

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:RECRUITING

Study ID

NCT05708885

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 90 Years

Sexes Eligible for Study:ALL

Accepts Healthy Volunteers:Yes

Standard Ages:ADULT, OLDER_ADULT

Inclusion Criteria	Exclusion Criteria
* Healthy subjects aged 18 to 90 years. * Patents with dysphagia but normal high resolution esophageal manometric findings defined by the Chicago classification.	* Anyone less than 18 years old. * Patients with recent head and neck cancer (\<1 month post-surgery or \<3 months post-chemo radiation. * Patients suffering from muscle diseases like muscular dystrophies, myopathies. * Patients with neuro-muscular junction disorders myasthenia gravis, Eaton-Lambert disorders. * Patients having history of allergy to lidocaine or barium. * Patients who are pregnant or lactating. * Patients who are medically unstable. * Patients who are unable to apply the exerciser independently or with the help of a caregiver. * Patients who lack cognition.

Inclusion Criteria

Exclusion Criteria

* Healthy subjects aged 18 to 90 years.
* Patents with dysphagia but normal high resolution esophageal manometric findings defined by the Chicago classification.

* Anyone less than 18 years old.
* Patients with recent head and neck cancer (\<1 month post-surgery or \<3 months post-chemo radiation.
* Patients suffering from muscle diseases like muscular dystrophies, myopathies.
* Patients with neuro-muscular junction disorders myasthenia gravis, Eaton-Lambert disorders.
* Patients having history of allergy to lidocaine or barium.
* Patients who are pregnant or lactating.
* Patients who are medically unstable.
* Patients who are unable to apply the exerciser independently or with the help of a caregiver.
* Patients who lack cognition.

Contacts and Locations

Study Contact

Reza Shaker, MD

CONTACT

4149556840

rshaker@mcw.edu

Mark Kern

CONTACT

4148053826

mkern@mcw.edu

Principal Investigator

Reza Shaker

PRINCIPAL_INVESTIGATOR

Medical College of Wisconsin

Study Locations (Sites)

Medical College of Wisconsin

Milwaukee, Wisconsin, 53086

United States

Collaborators and Investigators

Sponsor: Medical College of Wisconsin

Reza Shaker, PRINCIPAL_INVESTIGATOR, Medical College of Wisconsin

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-09-13

Study Completion Date2026-04

Study Record Updates

Study Start Date2022-09-13

Study Completion Date2026-04

Terms related to this study

Additional Relevant MeSH Terms

Dysphagia, Esophageal