External Pharyngeal Exerciser and Pharyngeal Phase of Swallowing

Description

This study of healthy young and elderly individuals is intended to assess the effects of pharyngeal exerciser on pharyngeal pressure phenomenon during swallowing. Our specific aim is to test if the pharyngeal exerciser increases the workload of muscles involved in pharyngeal phase of swallowing.

Conditions

Dysphagia

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Study Overview

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Study Details

Study overview

This study of healthy young and elderly individuals is intended to assess the effects of pharyngeal exerciser on pharyngeal pressure phenomenon during swallowing. Our specific aim is to test if the pharyngeal exerciser increases the workload of muscles involved in pharyngeal phase of swallowing.

Impact of External Pharyngeal Exerciser on Pharyngeal Phase of Swallowing

External Pharyngeal Exerciser and Pharyngeal Phase of Swallowing

Condition
Dysphagia
Intervention / Treatment

-

Contacts and Locations

Milwaukee

Medical College of Wisconsin, Milwaukee, Wisconsin, United States, 53086

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Healthy volunteers must be at least 18 years of age or older.
  • * Subjects with cervical spine disorders.
  • * Subjects with neurological disorders like dementia, cerebrovascular diseases other than Parkinson's Disease
  • * Subjects with carotid artery bruit or carotid vascular disorders.
  • * Subjects suffering from muscle diseases like muscular dystrophies, myopathies.
  • * Subjects with neuro-muscular junction disorders myasthenia gravis, Eaton-Lambert disorders.
  • * Subjects with any current esophageal symptoms like heartburn, dysphagia, chest pain or regurgitation.
  • * Subjects cannot have previous head or neck surgery or radiation.
  • * Subjects unable to tolerate nasal intubation.
  • * Subjects with significant bleeding disorders for whom nasal intubation has been deemed contraindicated.
  • * Subjects with a known upper airway or esophageal obstruction preventing the passage of the manometry probe.
  • * Subjects with autonomic dysfunction.
  • * Subjects having a history of allergy to lidocaine and barium.
  • * Subjects who are pregnant or lactating.
  • * Subjects who have advanced medical disorders (e.g.: chronic obstructive pulmonary disease (COPD), congestive heart failure, cirrhosis, cancer, chronic renal failure, etc.).
  • * Subjects who are medically unstable.

Ages Eligible for Study

18 Years to 85 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Medical College of Wisconsin,

Reza Shaker, MD, PRINCIPAL_INVESTIGATOR, Medical College of Wisconsin

Study Record Dates

2024-09-30