RECRUITING

OCT Eccentric Fixation and Amblyopia in Children

Conditions

Amblyopia eccentric fixation patching foveation therapy OCT

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The objectives of this proposal are to characterize the relationship between OCT eccentric fixation (OCT-EF), fixation eye movement (FEM), macular sensitivity in children with amblyopia.

Official Title

OCT Eccentric Fixation, Fixation Stability, and Amblyopia in Children

Quick Facts

Study Start:2023-01-25

Study Completion:2026-01-24

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:RECRUITING

Study ID

NCT05714449

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:4 Years to 16 Years

Sexes Eligible for Study:ALL

Accepts Healthy Volunteers:No

Standard Ages:CHILD

Inclusion Criteria	Exclusion Criteria
1. children with best-corrected visual acuity (BCVA) of 20/40 (equivalent to 0.3 logMAR) or worse in the amblyopic eye (ranging from 20/40 to 20/400), and interocular difference of BCVA was at least two logMAR lines, 2. ocular causes of amblyopia that were identified as refractive(i.e., anisometropic, strabismus, or strabismic-anisometropic. * Anisometropia included interocular difference of spherical equivalent \>=1D or interocular difference of astigmatism cylinder magnitude \>=1D; * strabismus included those with deviation \>=10PD or good alignment after prior strabismus surgery; * combined type included those who meet the criteria of both anisometropia and strabismus. * For the patching group, we will enroll 15 children with strabismic amblyopia who are prescribed patching treatment. Age: 4-12 years old. * For the foveation therapy group, we will enroll 15 children with strabismic amblyopia who are prescribed foveation therapies. Age: 8-16 years old.	* born before 32 weeks gestational age; * neurologic, developmental, or systemic illnesses known to be associated with ocular pathologies; * congenital or acquired macular pathology.

Inclusion Criteria

Exclusion Criteria

1. children with best-corrected visual acuity (BCVA) of 20/40 (equivalent to 0.3 logMAR) or worse in the amblyopic eye (ranging from 20/40 to 20/400), and interocular difference of BCVA was at least two logMAR lines,
2. ocular causes of amblyopia that were identified as refractive(i.e., anisometropic, strabismus, or strabismic-anisometropic.
* Anisometropia included interocular difference of spherical equivalent \>=1D or interocular difference of astigmatism cylinder magnitude \>=1D;
* strabismus included those with deviation \>=10PD or good alignment after prior strabismus surgery;
* combined type included those who meet the criteria of both anisometropia and strabismus.
* For the patching group, we will enroll 15 children with strabismic amblyopia who are prescribed patching treatment. Age: 4-12 years old.
* For the foveation therapy group, we will enroll 15 children with strabismic amblyopia who are prescribed foveation therapies. Age: 8-16 years old.

* born before 32 weeks gestational age;
* neurologic, developmental, or systemic illnesses known to be associated with ocular pathologies;
* congenital or acquired macular pathology.

Contacts and Locations

Study Contact

Jingyun Wang, PhD

CONTACT

2129385759

jwang@sunyopt.edu

Principal Investigator

Jingyun Wang

PRINCIPAL_INVESTIGATOR

SUNY College of Optmetry

Study Locations (Sites)

SUNY College of Optometry

New York, New York, 10036

United States

Collaborators and Investigators

Sponsor: State University of New York College of Optometry

Jingyun Wang, PRINCIPAL_INVESTIGATOR, SUNY College of Optmetry

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-01-25

Study Completion Date2026-01-24

Study Record Updates

Study Start Date2023-01-25

Study Completion Date2026-01-24

Terms related to this study

Keywords Provided by Researchers

eccentric fixation
amblyopia
patching
foveation therapy
OCT

Additional Relevant MeSH Terms

Amblyopia