RECRUITING

UPURS Trial for Patient-centered Management of Symptomatic Obstructing Stones

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

A prospective, non-blinded, randomized controlled trial studying the management of symptomatic ureteral stones. This study will compare upfront ureteroscopy vs observation and delayed intervention for patients presenting to the emergency department with a symptomatic ureteral stone.

Official Title

Upfront vs Postponed Ureteroscopy (UPURS) Trial for Patient-centered Management of Symptomatic Obstructing Stones

Quick Facts

Study Start:2023-08-23
Study Completion:2024-06
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05715086

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Presenting to the Emergency Department (ED)
  2. * Adult (\> 18 yo)
  3. * ≥5mm ureteral stone diagnosed on CT scan
  4. * Presence of symptoms (pain, nausea, vomiting, hematuria)
  1. * Strict indication for stent
  2. * Stone burden not amenable to Ureteroscopy (URS)
  3. * Dirty urine analysis (UA) or positive urine culture (UCx)
  4. * Transplant kidney
  5. * Presence of conduit
  6. * Comorbidities not optimized for surgery
  7. * Strong preference for surgery or observation

Contacts and Locations

Study Contact

Catherine Arevalo, BA
CONTACT
415-514-0918
catherine.arevalo@ucsf.edu
Heiko Yang, MD
CONTACT
heiko.yang@ucsf.edu

Principal Investigator

Thomas Chi, MD
PRINCIPAL_INVESTIGATOR
University of California, San Francisco

Study Locations (Sites)

University of California, San Francisco
San Francisco, California, 94143
United States

Collaborators and Investigators

Sponsor: University of California, San Francisco

  • Thomas Chi, MD, PRINCIPAL_INVESTIGATOR, University of California, San Francisco

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-08-23
Study Completion Date2024-06

Study Record Updates

Study Start Date2023-08-23
Study Completion Date2024-06

Terms related to this study

Keywords Provided by Researchers

  • Symptomatic ureteral stones

Additional Relevant MeSH Terms

  • Ureteral Stone