RECRUITING

Simultaneous Prospective Kidney Transplant Assessment in Combined Liver Kidney Candidates

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of the study is to determine how much a persons kidney function recovers after receiving a simultaneous liver kidney transplant. The investigators will be contacting patients with kidney dysfunction with estimated GFR between 25 and 40 (not on dialysis treatment) who are listed to receive a simultaneous liver kidney (SLK) transplant to look at this function recovery. The investigators hope to develop a criteria based on GFR measurement, kidney function calculations from native kidneys vs transplanted kidney and compare the contributions, and correlate with estimated GFR on basic metabolic panel (BMP: a blood test) to predict higher chances of recovery of native kidney function.

Official Title

Simultaneous Prospective Kidney Transplant Assessment in Combined Liver Kidney

Quick Facts

Study Start:2023-12-08
Study Completion:2025-02
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05717842

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. \> 18 years old
  2. 2. Listed for Liver Transplant for ESLD and Kidney Transplant (not on dialysis at time of transplant surgery)
  3. 3. Candidates with two native kidneys.
  4. 4. Willing to participate and sign informed consent form.
  1. 1. Unstable patients (e.g. in the ICU or those who are on Continuous Renal Replacement Therapy (CRRT) who cannot complete the nuclear medicine scan or those with AKI on Hemodialysis
  2. 2. Prior history of any solid organ transplant.
  3. 3. Those who are currently pregnant or breast feeding.
  4. 4. Patients who have Autosomal Dominant polycystic kidney disease

Contacts and Locations

Study Contact

Mary Balmes-Fenwick, B.S.
CONTACT
317-948-7772
mbalmes@iu.edu

Study Locations (Sites)

IU Health University Hospital
Indianapolis, Indiana, 46202
United States

Collaborators and Investigators

Sponsor: Indiana University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-12-08
Study Completion Date2025-02

Study Record Updates

Study Start Date2023-12-08
Study Completion Date2025-02

Terms related to this study

Keywords Provided by Researchers

  • Liver
  • Kidney

Additional Relevant MeSH Terms

  • Transplant