Study of PYX-201 in Solid Tumors

Description

The primary objectives of this study are to determine the recommended dose(s) of PYX-201 for participants with relapsed/refractory (R/R) solid tumors, and to determine the objective response rate (ORR) in participants treated with PYX-201 as a single agent.

Conditions

Solid Tumor, Advanced Solid Tumor

Study Overview

Study Details

Study overview

The primary objectives of this study are to determine the recommended dose(s) of PYX-201 for participants with relapsed/refractory (R/R) solid tumors, and to determine the objective response rate (ORR) in participants treated with PYX-201 as a single agent.

A First-in-Human, Open-label, Multicenter, Phase 1 Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of PYX-201 in Participants With Advanced Solid Tumors

Study of PYX-201 in Solid Tumors

Condition
Solid Tumor
Intervention / Treatment

-

Contacts and Locations

Scottsdale

HonorHealth Research Institute, Scottsdale, Arizona, United States, 85258

Denver

SCRI - HealthOne Denver, Denver, Colorado, United States, 80218

Sarasota

SCRI - Florida Cancer Specialists, Sarasota, Florida, United States, 34232

Chicago

University of Chicago Medicine, Chicago, Illinois, United States, 60637

Boston

Massachusetts General Hospital, Boston, Massachusetts, United States, 02114

Saint Louis

Washington University School of Medicine, Saint Louis, Missouri, United States, 63110-1010

Providence

Rhode Island Hospital, Providence, Rhode Island, United States, 02903

Dallas

NEXT Dallas, Dallas, Texas, United States, 75231

San Antonio

NEXT San Antonio, San Antonio, Texas, United States, 78229

Fairfax

NEXT Virginia, Fairfax, Virginia, United States, 22031

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

    Ages Eligible for Study

    18 Years to

    Sexes Eligible for Study

    ALL

    Accepts Healthy Volunteers

    No

    Collaborators and Investigators

    Pyxis Oncology, Inc,

    Study Record Dates

    2027-05