E-Cigarettes for Harm Reduction in Smokers With Opioid Use Disorder

Description

The purpose of this an open-label, randomized controlled trial study is to compare the effectiveness of electronic cigarettes (e-cigarettes/e-cigs) versus telehealth motivational counseling with combination nicotine replacement therapy (NRT) + telehealth counseling on combustible cigarettes smoking reduction among persons with opioid use disorder (OUD) in methadone and buprenorphine treatment programs (opioid use disorder treatment programs (OUDTP)). OUDTP patients are a population with exceptionally high combustible cigarettes smoking burden and yet limited success in achieving meaningful clinical outcomes in tobacco treatment. If effective, electronic cigarettes would provide an additional tool for tobacco harm reduction among this difficult-to-treat vulnerable population.

Conditions

Opioid Use Disorder, Cigarette Smoking

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Study Overview

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Study Details

Study overview

The purpose of this an open-label, randomized controlled trial study is to compare the effectiveness of electronic cigarettes (e-cigarettes/e-cigs) versus telehealth motivational counseling with combination nicotine replacement therapy (NRT) + telehealth counseling on combustible cigarettes smoking reduction among persons with opioid use disorder (OUD) in methadone and buprenorphine treatment programs (opioid use disorder treatment programs (OUDTP)). OUDTP patients are a population with exceptionally high combustible cigarettes smoking burden and yet limited success in achieving meaningful clinical outcomes in tobacco treatment. If effective, electronic cigarettes would provide an additional tool for tobacco harm reduction among this difficult-to-treat vulnerable population.

Effectiveness and Impact of Counseling Enhanced With Electronic Cigarettes for Harm Reduction in Smokers With Opioid Use Disorder

E-Cigarettes for Harm Reduction in Smokers With Opioid Use Disorder

Condition
Opioid Use Disorder
Intervention / Treatment

-

Contacts and Locations

Bronx

Albert Einstein College of Medicine, Bronx, New York, United States, 10461

New York

NYU Langone Health, New York, New York, United States, 10016

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Currently smokes 5 or more CPD
  • 2. Age ≥ 21 years
  • 3. Has a diagnosis of Opioid Use Disorder
  • 4. In OUDTP (buprenorphine or methadone) ≥ 12 weeks via self-report or EHR records
  • 5. Stable methadone or buprenorphine dose for two weeks via self-report or EHR records
  • 6. Interested in reducing combustible cigarette (CC) smoking but not necessarily trying to quit
  • 7. Own a mobile phone or have regular access to a mobile phone.
  • 8. Able to provide an additional contact to improve follow-up rates.
  • 1. Does not speak English or Spanish
  • 2. Are pregnant or breastfeeding
  • 3. Not able to provide consent
  • 4. Used tobacco products other than CC in the past 2 weeks (e.g., EC, cigarillo)
  • 5. Currently engaged in an attempt to quit CC smoking
  • 6. Reports having severe chronic obstructive pulmonary disease or asthma (i.e., with exacerbation requiring hospitalization or intubation in the prior 6 months)
  • 7. Reports current major depressive or manic episode, current psychotic disorder, past-year suicide attempt or psychiatric hospitalization, or current suicidal ideation with plan or intent.

Ages Eligible for Study

21 Years to 75 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

NYU Langone Health,

Omar El-Shahawy, PRINCIPAL_INVESTIGATOR, NYU Langone Health

Study Record Dates

2027-03