RECRUITING

Ocular Blood Flow Imaging for Glaucoma Assessment

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this clinical trial is to investigate the use of an FDA-cleared retinal blood flow imaging instrument called the XyCAM RI and XyCAM FC (Vasoptic Medical, Inc., Columbia, MD) in glaucoma management. The main question it aims to answer are: * Can the investigators use blood flow to discriminate between eyes with early-stage glaucoma and variable-matched controls? * Can the investigators validate that the XyCAM FC simultaneously captures both stereo fundus photography and ocular blood flow monitoring? Participants will be * measured for their blood pressure, heart rate, height, and weight * dilated with tropicamide * imaged using the XyCAM RI, fundus photography, optical coherence tomography, and standard automated perimetry * imaged using the XyCAM RI while inhaling 100% oxygen through a mask

Official Title

Ocular Blood Flow Imaging for Glaucoma Assessment

Quick Facts

Study Start:2023-03-30
Study Completion:2025-04-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05726058

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 88 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Age 18 and older with binocular vision
  2. * Able to provide informed consent
  3. * Patient is a healthy control OR is recommended for glaucoma assessment OR diagnosed with moderate to severe glaucoma in at least one eye as determined by Hodapp Anderson Criteria
  1. * The subject has significant media opacity (e.g., a visually significant cataract or significant corneal scar)
  2. * The subject has previous ocular surgery other than uncomplicated cataract extraction, laser trabeculoplasty (ALT or SLT), or YAG capsulotomy
  3. * The subject has prior ocular disease other than glaucoma
  4. * The subject has anatomically narrow angles or a prior adverse reaction to administration of Tropicamide or fluorescein dye
  5. * The subject has more than 15 diopters of refractive error
  6. * The subject is a female who is pregnant or nursing
  7. * The subject has diabetes mellitus

Contacts and Locations

Study Contact

Osamah J Saeedi, MD, MS
CONTACT
(410) 328-5929
osaeedi@som.umaryland.edu

Principal Investigator

Grace Forbes, MS
STUDY_DIRECTOR
University of Maryland, Baltimore

Study Locations (Sites)

University of Maryland Eye Associates at Redwood
Baltimore, Maryland, 21201
United States

Collaborators and Investigators

Sponsor: University of Maryland, Baltimore

  • Grace Forbes, MS, STUDY_DIRECTOR, University of Maryland, Baltimore

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-03-30
Study Completion Date2025-04-30

Study Record Updates

Study Start Date2023-03-30
Study Completion Date2025-04-30

Terms related to this study

Keywords Provided by Researchers

  • glaucoma
  • xycam
  • blood flow
  • imaging
  • ophthalmology
  • retinal blood flow
  • eye disease

Additional Relevant MeSH Terms

  • Glaucoma