Vertical Soft Tissue Augmentation With CTG vs ADM

Description

The study aims at comparing two different approaches for vertical soft tissue augmentation at implant sites exhibiting soft tissue dehiscences: autogenous connective tissue graft vs acellular dermal matrix + enamel matrix derivative

Conditions

Implant Complication

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Study Overview

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Study Details

Study overview

The study aims at comparing two different approaches for vertical soft tissue augmentation at implant sites exhibiting soft tissue dehiscences: autogenous connective tissue graft vs acellular dermal matrix + enamel matrix derivative

Vertical Soft Tissue Augmentation With Dermal Matrix and Enamel Matrix Derivative vs Connective Tissue Graft for the Treatment of Peri-implant Soft Tissue Dehiscences in the Esthetic Zone: A Randomized, Controlled, Clinical, Trial

Vertical Soft Tissue Augmentation With CTG vs ADM

Condition
Implant Complication
Intervention / Treatment

-

Contacts and Locations

Boston

Harvard School of Dental Medicine, Boston, Massachusetts, United States, 02115

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Age ≥ 18 years
  • * Periodontally and systemically healthy
  • * Full-mouth plaque score and full-mouth bleeding score ≤ 20% (measured at four sites per tooth)
  • * Presence of single functional dental implant in the anterior with a PSTD
  • * Implants diagnosed as healthy (Berglundh et al., 2018)
  • * Contraindications for surgery
  • * Systemic condition (e.g. diabetes mellitus, HIV, cancer, etc) that could compromise wound healing
  • * Patients pregnant or attempting to get pregnant (self-reported)
  • * Untreated periodontitis
  • * Untreated peri-implant mucositis or peri-implantitis (Berglundh et al., 2018)
  • * Smoking, defined as self-reported daily habit. Occasional smokers won't be excluded
  • * History of soft tissue grafting at the implant site within the last 6 months

Ages Eligible for Study

18 Years to 99 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Harvard Medical School (HMS and HSDM),

Lorenzo Tavelli, DDS, MS, PRINCIPAL_INVESTIGATOR, Harvard School of Dental Medicine, Boston, USA

Study Record Dates

2026-11-27