Steroids in Occipital Nerve Block for Treatment of Headache

Description

Currently there is limited evidence of benefit for the addition of steroids to occipital nerve blocks for treatment of headache, and not all steroids have been explored. The purpose of this research is to learn more about whether the addition of a specific kind of steroid (dexamethasone) provides any additional benefit to nerve blocks.

Conditions

Headache, Occipital Nerve Block

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Study Overview

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Study Details

Study overview

Currently there is limited evidence of benefit for the addition of steroids to occipital nerve blocks for treatment of headache, and not all steroids have been explored. The purpose of this research is to learn more about whether the addition of a specific kind of steroid (dexamethasone) provides any additional benefit to nerve blocks.

Treatment of Headache With Occipital Nerve Blocks: Comparison Trial of Anesthetic With or Without Dexamethasone

Steroids in Occipital Nerve Block for Treatment of Headache

Condition
Headache
Intervention / Treatment

-

Contacts and Locations

Rochester

Mayo Clinic Minnesota, Rochester, Minnesota, United States, 55905

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Treated for headache including but not limited to occipital neuralgia, episodic migraine, chronic migraine and/or cervicogenic headache.
  • * Stable on preventative medication dosing for at least 1 month prior to occipital nerve block and no change in preventative medication regimen during the course of the study.
  • * Able to understand the requirements of the study and return for treatment.
  • * Able to independently provide informed consent.
  • * Diagnosis of cluster headache according to the International Classification of Headache Disorders 3rd edition.
  • * Occipital or other cranial nerve block administered within 3 months prior to initiation of study.
  • * History of adverse reaction or contraindication to any of the study ingredients (bupivacaine, lidocaine, dexamethasone).
  • * Pregnancy.
  • * Infection or bleeding at site of injection.
  • * Cranial bone or cervical spine defects/prior surgeries near injection site that prohibit use of landmark-based technique.

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Mayo Clinic,

Carrie Robertson, MD, PRINCIPAL_INVESTIGATOR, Mayo Clinic

Study Record Dates

2024-12