Counseling for Harm Reduction and Retention in Medication-assisted Treatment - Cherokee Nation

Description

The goal of this randomized clinical trial is to test the efficacy of a program meant to enhance Counseling for Harm Reduction and Retention in MAT in Cherokee Nation (CHaRRM-CN). The main questions it aims to answer are whether CHaRRM-CN: improves retention of patients in MAT, decreases substance-related harm and illicit opioid use, and increases cultural connectedness. After providing written, informed consent, participants will attend a baseline assessement and will then be randomized to either the CHaRRM-CN or treatment as usual group. For 6 months after randomization, participants will be exposed to CHaRRM-CN or treatment as usual. During that time, participants will also attend the 1-month, 3-month and 6-month follow-ups to track their progress through the programs. After the 6 months of either treatment condition, investigators will compare the groups to see if they differ on retention, substance-use outcomes and Native enculturation.

Conditions

Opioid Use Disorder

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Study Overview

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Study Details

Study overview

The goal of this randomized clinical trial is to test the efficacy of a program meant to enhance Counseling for Harm Reduction and Retention in MAT in Cherokee Nation (CHaRRM-CN). The main questions it aims to answer are whether CHaRRM-CN: improves retention of patients in MAT, decreases substance-related harm and illicit opioid use, and increases cultural connectedness. After providing written, informed consent, participants will attend a baseline assessement and will then be randomized to either the CHaRRM-CN or treatment as usual group. For 6 months after randomization, participants will be exposed to CHaRRM-CN or treatment as usual. During that time, participants will also attend the 1-month, 3-month and 6-month follow-ups to track their progress through the programs. After the 6 months of either treatment condition, investigators will compare the groups to see if they differ on retention, substance-use outcomes and Native enculturation.

Counseling for Harm Reduction and Retention in Medication-assisted Treatment - Cherokee Nation

Counseling for Harm Reduction and Retention in Medication-assisted Treatment - Cherokee Nation

Condition
Opioid Use Disorder
Intervention / Treatment

-

Contacts and Locations

Tahlequah

Cherokee Nation Health Services, Tahlequah, Oklahoma, United States, 74464

Seattle

University of Washington School of Medicine, Seattle, Washington, United States, 98195

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. At least 18 years of age
  • 2. Must be newly registered (within 4 weeks) in the CNHS MAT Program. (Prior patients can participate as long as their most recent treatment course was at least 6 months prior).
  • 3. Must be willing to provide written informed consent to enroll in this study
  • 1. Refusal or inability to consent to participation in research. (The latter is assessed using the UCSD Brief Assessment of Capacity to Consent.)
  • 2. Refusal or inability to consent and constituting a risk to the safety and security of other patients or staff

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Washington State University,

Lonnie A Nelson, PhD, PRINCIPAL_INVESTIGATOR, Washington State University

Susan E Collins, PhD, PRINCIPAL_INVESTIGATOR, University of Washington

Ashley Lincoln, MSW, PRINCIPAL_INVESTIGATOR, Cherokee Nation Health Services

Study Record Dates

2025-07-31