Interstage Monitoring Using an Implantable Loop Recorder: A Pilot Study

Description

The primary objective of this investigation is to evaluate the feasibility and safety of implantable loop recorder implantation (using the LUX-DX™) in newborns undergoing stage 1 palliation. The secondary objective of the investigation is to evaluate the feasibility of continuous measurement of heart rate and arrhythmia using an implantable loop recorder (LUX-Dx™) during the interstage period. An implantable loop recorder will be placed at the time of chest closure following stage 1 palliation (either at the time of index surgery or delayed). The device will be placed in a subclavicular pouch through the existing sternotomy incision. Participants will be in the study for 6 months to 3 years.

Conditions

Univentricular Heart

Study Overview

Study Details

Study overview

The primary objective of this investigation is to evaluate the feasibility and safety of implantable loop recorder implantation (using the LUX-DX™) in newborns undergoing stage 1 palliation. The secondary objective of the investigation is to evaluate the feasibility of continuous measurement of heart rate and arrhythmia using an implantable loop recorder (LUX-Dx™) during the interstage period. An implantable loop recorder will be placed at the time of chest closure following stage 1 palliation (either at the time of index surgery or delayed). The device will be placed in a subclavicular pouch through the existing sternotomy incision. Participants will be in the study for 6 months to 3 years.

Interstage Monitoring Using an Implantable Loop Recorder: A Pilot Study

Interstage Monitoring Using an Implantable Loop Recorder: A Pilot Study

Condition
Univentricular Heart
Intervention / Treatment

-

Contacts and Locations

Boston

Boston Children's Hospital, Boston, Massachusetts, United States, 02115

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Patients with single ventricle physiology undergoing stage 1 palliation in the 1st month of life
  • * Prematurity (\<36 weeks gestational age)
  • * Birth weight \<2.5 kg
  • * Hybrid stage 1 palliation (patent ductus arteriosus stenting, bilateral pulmonary artery bands)
  • * Presence and/or need for devices sensitive to magnetic fields such as hearing aids, pacemaker, and other implanted devices.
  • * Clinical team does not think that the patient is a good candidate

Ages Eligible for Study

to 30 Days

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Boston Children's Hospital,

Study Record Dates

2027-09-10