RECRUITING

rTMS and Rehabilitation for Individuals With CRPS Type 1

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Subjects with complex regional pain syndrome (CRPS) Type 1 will be randomized to receive repeated transcranial magnetic stimulation (rTMS) followed by rehabilitation or sham rTMS followed by rehabilitation. Treatment will last for 4 weeks, with the first week including 4 rTMS treatments and 2 rehabilitation treatments. Subsequent weeks will include 2 rTMS treatments followed by 2 rehabilitation treatments. Outcome measures will include pain ratings, PROMIS questionnaires, global rating of change, and grip strength or 1 repetition maximum leg press.

Official Title

Repeated Transcranial Magnetic Stimulation and Rehabilitation for Individuals With Complex Regional Pain Syndrome Type 1

Quick Facts

Study Start:2023-02-28
Study Completion:2025-08-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05745025

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Upper or lower extremity CRPS Type 1 (also called RSD-Reflex Sympathetic Dystrophy) of at least 6 months.
  2. * Pain rating on NPRS of at least 4/10
  3. * No initiation of a new intervention (i.e., medication, rehab, injections) in the previous 2 months.
  4. * No plan to initiate a new intervention during the study treatment timeframe (4 weeks).
  1. * A history of seizures or epilepsy
  2. * Intracranial metallic devices
  3. * Pacemaker
  4. * Intrathecal infusion pumps
  5. * Brain or spinal cord stimulators with epidural electrodes
  6. * Other ferromagnetic metallic intracranial implants
  7. * Apparent mental or psychiatric disorder that prevents adequate informed consent
  8. * Current pregnancy
  9. * Non-English speaking

Contacts and Locations

Study Contact

Adam P Rufa, DPT, PhD
CONTACT
(315)464-6883
rufaa@upstate.edu

Principal Investigator

Adam Rufa, DPT, PhD
PRINCIPAL_INVESTIGATOR
SUNY Upstate Medical Univerity

Study Locations (Sites)

SUNY Upstate Medical Univeristy Institute of Human Performance
Syracuse, New York, 13210
United States

Collaborators and Investigators

Sponsor: State University of New York - Upstate Medical University

  • Adam Rufa, DPT, PhD, PRINCIPAL_INVESTIGATOR, SUNY Upstate Medical Univerity

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-02-28
Study Completion Date2025-08-01

Study Record Updates

Study Start Date2023-02-28
Study Completion Date2025-08-01

Terms related to this study

Additional Relevant MeSH Terms

  • Complex Regional Pain Syndrome Type I