Functional Brain Mapping for Patients With Epilepsy

Description

We aim to determine the clinical utility of 'dynamic tractography': a novel method for visualizing electrical neural transfers that incorporates the underlying white matter tracts and supporting linguistic processing. We will also determine how well objective electrophysiology biomarkers will improve the prediction of language outcomes following epilepsy surgery. This project will ultimately optimize understanding of how the human brain develops its language network dynamics.

Conditions

Epilepsy

Study Overview

Study Details

Study overview

We aim to determine the clinical utility of 'dynamic tractography': a novel method for visualizing electrical neural transfers that incorporates the underlying white matter tracts and supporting linguistic processing. We will also determine how well objective electrophysiology biomarkers will improve the prediction of language outcomes following epilepsy surgery. This project will ultimately optimize understanding of how the human brain develops its language network dynamics.

Functional Brain Mapping in Pediatric Neurosurgery

Functional Brain Mapping for Patients With Epilepsy

Condition
Epilepsy
Intervention / Treatment

-

Contacts and Locations

Detroit

Children's Hospital of Michigan, Detroit, Michigan, United States, 48201

Detroit

Wayne State University, Detroit, Michigan, United States, 48201

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Epilepsy surgery with extraoperative intracranial EEG recording with subdural or depth electrodes.
  • * Patients with a malignant brain tumor, or progressive neurodegenerative or metabolic disorders who are not considered candidates for intracranial EEG recording.

Ages Eligible for Study

6 Months to 21 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Wayne State University,

Eishi Asano, MD, PhD, PRINCIPAL_INVESTIGATOR, Wayne State University

Study Record Dates

2027-03-31