PRospective Evaluation of Peripartum Anticoagulation ManaGement for ThrOmboembolism

Description

The PREP and GO study is an international multicentre prospective cohort evaluating anticoagulation management strategies around labor and delivery and the postpartum period.

Conditions

Pregnancy Related, Venous Thromboembolism

Talk to us

Study Overview

On this page

Study Details

Study overview

The PREP and GO study is an international multicentre prospective cohort evaluating anticoagulation management strategies around labor and delivery and the postpartum period.

A Prospective Cohort Study Evaluating Peripartum Anticoagulation Management Among Pregnant Women with Venous Thromboembolism and Its Impact on Patient Outcomes

PRospective Evaluation of Peripartum Anticoagulation ManaGement for ThrOmboembolism

Condition
Pregnancy Related
Intervention / Treatment

-

Contacts and Locations

Durham

Duke University Hospital, Durham, North Carolina, United States, 27710

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * 18 years of age or older
  • * Requires anticoagulation during the antepartum period of pregnancy for a VTE indication, including at least one of:
  • 1. Objectively confirmed VTE (DVT, superficial vein thrombosis \[SVT\], PE or unusual site thrombosis) diagnosed during the current pregnancy;
  • 2. Objectively confirmed VTE diagnosed in a prior pregnancy;
  • 3. Objectively confirmed VTE diagnosed when not pregnant;
  • 4. Inherited or acquired thrombophilia requiring anticoagulation.
  • * Receiving any dose or type of LMWH during the antepartum period
  • * Anticoagulation for a non-VTE indication, including prosthetic heart valves, atrial fibrillation, prevention of placenta-mediated pregnancy complications, or prevention of recurrent pregnancy loss (participants can be included with a diagnosis of antiphospholipid syndrome (APS) with or without thrombotic events)
  • * Unable to provide or declined consent.
  • * Home or birthing centre planned delivery.

Ages Eligible for Study

18 Years to 60 Years

Sexes Eligible for Study

FEMALE

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Calgary,

Leslie Skeith, MD, PRINCIPAL_INVESTIGATOR, University of Calgary

Isabelle Malhamé, MD, PRINCIPAL_INVESTIGATOR, McGill University

Kinga Malinowski, MD, PRINCIPAL_INVESTIGATOR, University of Toronto

Study Record Dates

2029-12-31