RECRUITING

Blood Pressure Variability and Ischemic Stroke Outcome

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this observational study is to evaluate the role of blood pressure (BPV) variability in patients suffering from acute ischemic stroke. The main questions it aims to answer are: 1. To determine the association of BPV with functional/cognitive outcome after ischemic stroke. 2. To determine a pathophysiologic mechanism of BPV's deleterious effect on functional outcome. 3. To evaluate potential treatment targets to pharmacologically reduce BPV after ischemic stroke.

Official Title

Blood Pressure Variability and Ischemic Stroke Outcome

Quick Facts

Study Start:2024-07-15
Study Completion:2026-03-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05756257

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Ischemic stroke according to the American Heart Association (AHA) definition and either:
  2. 1. CT or MRI showing ischemic stroke in the anterior circulation (frontal, parietal or superior temporal lobes), or
  3. 2. Occlusion of the internal carotid, middle cerebral or anterior cerebral arteries on computed tomography angiography (CTA) or magnetic resonance angiography (MRA)
  1. * Pre-morbid mRS ≥3
  2. * Predicted hospital system admission \<72 hours
  3. * Pacemaker or other MRI contraindications per American College of Radiology guidelines

Contacts and Locations

Study Contact

Adam de Havenon, MD
CONTACT
203-785-4085
adam.dehavenon@yale.edu

Principal Investigator

Adam de Havenon, MD
PRINCIPAL_INVESTIGATOR
Yale University

Study Locations (Sites)

Yale-New Haven Hospital
New Haven, Connecticut, 06510
United States
University of Chicago Medical Center
Chicago, Illinois, 60637
United States
Massachusetts General Hospital
Boston, Massachusetts, 02114
United States

Collaborators and Investigators

Sponsor: Yale University

  • Adam de Havenon, MD, PRINCIPAL_INVESTIGATOR, Yale University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-07-15
Study Completion Date2026-03-30

Study Record Updates

Study Start Date2024-07-15
Study Completion Date2026-03-30

Terms related to this study

Additional Relevant MeSH Terms

  • Acute Ischemic Stroke
  • Blood Pressure Variability