Aldosterone Renin Ratio (ARR) Test to Increase Case-detection of Primary Aldosteronism (PA)

Description

The mission of this project is to increase the detection of Primary Aldosteronism (PA), the most common cause of secondary hypertension, which can either be cured surgically or treated with targeted medications.

Conditions

Primary Aldosteronism

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Study Overview

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Study Details

Study overview

The mission of this project is to increase the detection of Primary Aldosteronism (PA), the most common cause of secondary hypertension, which can either be cured surgically or treated with targeted medications.

Aldosterone Renin Ratio (ARR) Test to Increase Case-detection of Primary Aldosteronism (PA)

Aldosterone Renin Ratio (ARR) Test to Increase Case-detection of Primary Aldosteronism (PA)

Condition
Primary Aldosteronism
Intervention / Treatment

-

Contacts and Locations

Cleveland

The Cleveland Clinic Foundation, Cleveland, Ohio, United States, 44195

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Consent to participate in the study
  • * Participants limited to subjects in the CCF
  • * Age between and inclusive of 18 and 65 years of age
  • * No gender exclusion
  • * Patients diagnosed with Essential Hypertension by ICD-10 code on at least two occasions in the previous six months, even if not on medications for hypertension
  • * Patients on a single anti-hypertensive medication for at least six months with the diagnosis of hypertension
  • * Those on a mineralocorticoid antagonist therapy (spironolactone, eplerenone)
  • * Those with a documented diagnosis of primary aldosteronism or primary hyperaldosteronism
  • * Those with a diagnosis of secondary hyperaldosteronism
  • * Those with a diagnosis of heart failure, renal artery stenosis, cirrhosis, ascites, cor pulmonale.
  • * Pregnancy status (verbal)

Ages Eligible for Study

18 Years to 65 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

The Cleveland Clinic,

Study Record Dates

2025-08-29