RECRUITING

PROton Therapy for Post Surgical Treatment of GYNecologic Cancer

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This is a single institution, multi-center, Phase II, single-arm study, using Whole Pelvis (WP) Pencil Beam Scanning Proton Radiation (PBS PRT) in the post-surgical, adjuvant setting for definitive treatment of gynecologic cancers. The purpose of this study is to estimate rate of acute clinician-reported gastrointestinal (GI) toxicity using WP PBS PRT in the definitive treatment of gynecologic cancers in the post-surgical, adjuvant setting.

Official Title

Adjuvant Proton Whole Pelvis Radiation Therapy for Treatment of Post-Surgical Gynecologic Cancers

Quick Facts

Study Start:2023-11-06
Study Completion:2026-11
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05758688

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Histologically confirmed cervical or endometrial cancer
  2. * Indication for adjuvant whole pelvic radiation therapy, with or without systemic therapy
  3. * Age of 18 years or older
  4. * Written informed consent
  5. * ECOG of 0-2 within 3 months of enrolling
  1. * Prior course of pelvic radiation
  2. * Metastatic disease outside of the pelvis
  3. * Active inflammatory bowel disease
  4. * Incapacity to provide informed consent

Contacts and Locations

Study Contact

Project Manager
CONTACT
215-662-3790
RadOncCRU@PennMedicine.upenn.edu

Principal Investigator

Neil K Taunk, MD, MSCTS
PRINCIPAL_INVESTIGATOR
University of Pennsylvania

Study Locations (Sites)

Lancaster General Health - Ann B. Barshinger Cancer Institute
Lancaster, Pennsylvania, 17601
United States
University of Pennsylvania
Philadelphia, Pennsylvania, 19104
United States

Collaborators and Investigators

Sponsor: Abramson Cancer Center at Penn Medicine

  • Neil K Taunk, MD, MSCTS, PRINCIPAL_INVESTIGATOR, University of Pennsylvania

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-11-06
Study Completion Date2026-11

Study Record Updates

Study Start Date2023-11-06
Study Completion Date2026-11

Terms related to this study

Additional Relevant MeSH Terms

  • Cervical Cancer
  • Uterine Cancer
  • Endometrial Cancer