Developing an Opioid Taper Intervention Before Total Joint Arthroplasty

Description

The goal of this clinical trial is to develop an pharmacist-led preoperative opioid taper intervention for patients undergoing total knee or hip replacement who are on chronic opioids before their surgery. The main questions it aims to answer are: * Is the intervention feasible and acceptable to patients? * Does the intervention result in a decrease in opioid dose during the preoperative period? Participants will meet with a clinical pharmacist, who will provide some basic education on pain and opioids, and will propose an opioid taper schedule. The pharmacist will then follow-up with the participant by phone each week until surgery to assess progress and adjust the taper as necessary.

Conditions

Arthritis Knee, Arthritis Hip, Chronic Pain

Study Overview

Study Details

Study overview

The goal of this clinical trial is to develop an pharmacist-led preoperative opioid taper intervention for patients undergoing total knee or hip replacement who are on chronic opioids before their surgery. The main questions it aims to answer are: * Is the intervention feasible and acceptable to patients? * Does the intervention result in a decrease in opioid dose during the preoperative period? Participants will meet with a clinical pharmacist, who will provide some basic education on pain and opioids, and will propose an opioid taper schedule. The pharmacist will then follow-up with the participant by phone each week until surgery to assess progress and adjust the taper as necessary.

Developing and Testing an Opioid Taper Intervention Before Total Knee Arthroplasty: Phase 2 Intervention Development

Developing an Opioid Taper Intervention Before Total Joint Arthroplasty

Condition
Arthritis Knee
Intervention / Treatment

-

Contacts and Locations

Birmingham

UAB Hospital-Highlands, Birmingham, Alabama, United States, 35205

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * decided to pursue primary, unilateral total knee or hip arthroplasty with planned surgery date in 4-8 weeks
  • * currently taking between 20 and 90 MME of oral opioids, and that dose has been stable for at least 3 months
  • * have a reliable telephone number for contact
  • * speaks English
  • * Taking opioid medications that include:
  • * Buprenorphine
  • * Methadone
  • * Long-acting formulations of opioid pain medications (e.g., extended-release oxycodone and extended-release morphine)
  • * Transdermal formations of opioid pain medications (e.g., fentanyl patches)

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Alabama at Birmingham,

Kevin R Riggs, MD, PRINCIPAL_INVESTIGATOR, University of Alabama at Birmingham

Study Record Dates

2025-03-03