RECRUITING

Stress & Self-Control Costs

Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Self-control failures are a universal challenge for healthy and clinical populations. Recent work suggests these failures may arise from excessive cognitive costs associated with exercising self-control, yet the mechanisms underlying these costs are unknown. To address this, the investigators will use a validated decision-making task that measures how much individuals will pay (from a study endowment) to restrict access to tempting rewards that may lead to self-control failures. The investigators will examine these costs to identify their cognitive, neural and affective mechanisms. First, the investigators will identify the cognitive and computational mechanism that gives rise to self-control costs. Second, the investigators will characterize the neural correlates of self-control costs and identify neural mediators and connectivity patterns stemming from these costs. Finally, the investigators will examine how different classes of stressors (physical, social, or lifetime stress) shape the behavioral and neural representations of self-control costs.

Official Title

Neural and Affective Mechanisms Underlying Prospective Self-control Costs

Quick Facts

Study Start:2024-10-01
Study Completion:2028-04-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05795179

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 70 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * 18-70 years of age, able to speak, read, and write fluently in English
  2. * be willing and able to follow study procedures and provide informed consent.
  3. * Must additionally confirm they are on a diet to maintain/lose weight and are implementing/maintaining dietary changes.
  1. * History of or medication for neurologic or psychiatric disease
  2. * High-blood pressure or heart condition
  3. * Diabetes, food allergies, metabolic disorders or history of eating disorder
  4. * Use of corticosteroids or beta-blockers
  5. * Metallic implants or devices contraindicating magnetic resonance imaging.
  6. * Pregnancy is considered an exclusion criteria due to all stress and scanning procedures, thus pregnant participants will not be permitted to participate in the study.

Contacts and Locations

Study Contact

Candace Raio
CONTACT
candace.raio@nyulangone.org

Principal Investigator

Candace Raio
PRINCIPAL_INVESTIGATOR
NYU Langone Health

Study Locations (Sites)

NYU Langone Health
New York, New York, 10016
United States

Collaborators and Investigators

Sponsor: NYU Langone Health

  • Candace Raio, PRINCIPAL_INVESTIGATOR, NYU Langone Health

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-10-01
Study Completion Date2028-04-01

Study Record Updates

Study Start Date2024-10-01
Study Completion Date2028-04-01

Terms related to this study

Additional Relevant MeSH Terms

  • Self-Control