Floatation-REST in Methamphetamine Use Disorder: A Pilot Study

Description

This early-stage trial aims to examine the feasibility, tolerability, and safety of Floatation-REST (Reduced Environmental Stimulation Therapy) or an active comparison condition in 50 individuals receiving treatment for Amphetamine-Type Substance Use Disorder.

Conditions

Amphetamine-Type Substance Use Disorder

Study Overview

Study Details

Study overview

This early-stage trial aims to examine the feasibility, tolerability, and safety of Floatation-REST (Reduced Environmental Stimulation Therapy) or an active comparison condition in 50 individuals receiving treatment for Amphetamine-Type Substance Use Disorder.

Reduced Environmental Stimulation Therapy (REST) in Methamphetamine Use Disorder: A Pilot Study

Floatation-REST in Methamphetamine Use Disorder: A Pilot Study

Condition
Amphetamine-Type Substance Use Disorder
Intervention / Treatment

-

Contacts and Locations

Tulsa

Laureate Institute for Brain Research, Tulsa, Oklahoma, United States, 74136

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Between 18-55 years of age
  • * Meeting criteria for a primary DSM-5 diagnosis of current methamphetamine use disorder
  • * Has completed at least two weeks of inpatient treatment (translating into having at least two weeks of drug/alcohol sobriety) at one of the two recruitment sites (Grand Addiction and Recovery Center or Women In Recovery) and is still currently enrolled in this treatment at the time of the study
  • * Capable of completing all measures during each session of the experiment: able to provide written informed consent and must have sufficient proficiency in the English language to understand and complete interviews, questionnaires, and all other study procedures.
  • * Has any of the following DSM-5 disorders: Schizophrenia Spectrum and Other Psychotic Disorders OR Bipolar I Disorder
  • * Participant fails to adhere to our "Pre-float checklist".
  • * Any antihistamine that causes drowsiness (e.g., Benadryl).
  • * Caffeine or nicotine consumed within the past 2 hours.
  • * Reports a history of unstable liver or renal insufficiency; glaucoma; diabetes; significant and unstable cardiac, vascular, pulmonary, gastrointestinal, endocrine, neurologic, hematologic, rheumatologic, or metabolic disturbance; or any other condition that, in the opinion of the investigator, would make participation not be in the best interest (e.g., compromise the well-being) of the subject or that could prevent, limit, or confound the protocol-specified assessments.
  • * A breathalyzer test positive for alcohol or a drug-positive urine test at either session.
  • * Non-correctable vision or hearing problems.
  • * Unwillingness or inability to complete major aspects of the study protocol (e.g., floating). However, failing to complete some individual aspects will be acceptable (e.g., being unwilling to answer individual items on a questionnaire).

Ages Eligible for Study

18 Years to 55 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Laureate Institute for Brain Research, Inc.,

Study Record Dates

2024-08-01