A Study of Magnesium and Bladder Spasms Following Ambulatory Urologic Procedures

Description

This research is being done to find out whether intravenous magnesium is effective in the treatment of bladder spasms after urologic surgery.

Conditions

Bladder Spasms

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Study Overview

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Study Details

Study overview

This research is being done to find out whether intravenous magnesium is effective in the treatment of bladder spasms after urologic surgery.

Magnesium and Bladder Spasms Following Ambulatory Urologic Procedures

A Study of Magnesium and Bladder Spasms Following Ambulatory Urologic Procedures

Condition
Bladder Spasms
Intervention / Treatment

-

Contacts and Locations

Rochester

Mayo Clinic in Minnesota, Rochester, Minnesota, United States, 55905

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Are unable to grant informed consent or comply with study procedure.
  • * Allergy or known sensitivity to magnesium or Renacidin.
  • * Expected or high risk of bladder extravasation.
  • * Ongoing atrial fibrillation prior to surgery.
  • * Are undergoing emergency surgery.
  • * Are pregnant.
  • * Known hypermagnesemia.
  • * Patients with neuromuscular weakness (e.g., Myasthenia gravis) due to magnesium's muscle weakening effect.
  • * Patients with myocardial compromise or cardiac conduction defects because of magnesium's anti-inotropic effects.
  • * Patients with renal insufficiency, glomerular filtration rate less than 30, since Magnesium is eliminated by the kidneys resulting in exaggerated rise in serum magnesium.
  • * Patients with concomitant use of a calcium channel blocker since magnesium sulfate could act synergistically to suppress muscular contractility.

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Mayo Clinic,

Gregory Nuttall, MD, PRINCIPAL_INVESTIGATOR, Mayo Clinic

Study Record Dates

2025-12-31