Low Energy Availability and Pituitary Function (LEAP Study)

Description

The purpose of this study is to learn more about reproductive hormones and if they change in response to 5-days eating an individualized, standardized diet at two levels: energy balance and low energy intake.

Conditions

Hypogonadotropic Hypogonadism

Study Overview

Study Details

Study overview

The purpose of this study is to learn more about reproductive hormones and if they change in response to 5-days eating an individualized, standardized diet at two levels: energy balance and low energy intake.

A Randomized Cross-over Study of Low Energy Availability on Pituitary Function in Women

Low Energy Availability and Pituitary Function (LEAP Study)

Condition
Hypogonadotropic Hypogonadism
Intervention / Treatment

-

Contacts and Locations

Aurora

University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States, 80045

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Female
  • * Age 18-30
  • * Body mass index between 18.5-24.9 OR 30-45
  • * Have regular menstrual cycles between 18-40 days over the past 6 months
  • * Weight stable (not gained or lost 5kg) in the past 3 months
  • * Using hormonal birth control currently or within the past three months
  • * Polycystic ovary syndrome (current or past diagnosis)
  • * Pregnant, lactating, planning to become pregnant in next 6 months
  • * Engaging in regular intentional aerobic exercise
  • * Significant medical issues (e.g.,cardiovascular disease or diabetes)

Ages Eligible for Study

18 Years to 30 Years

Sexes Eligible for Study

FEMALE

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Colorado, Denver,

Ann E Caldwell, PhD, PRINCIPAL_INVESTIGATOR, University of Colorado Anschutz School of Medicine

Study Record Dates

2025-01