RECRUITING

Brain Connectivity Changes With Spinal Cord Stimulation and Treatment of Chronic Pain: A Resting State NIRS/EEG Study

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study aims to assess how use of spinal cord stimulation for the treatment of chronic pain impacts brain structure and function. The investigators will use a non-invasive neuroimaging technique called resting state Near Infrared Spectroscopy and Electroencephalography (rs-fNIRS/EEG). The investigators will enroll Veterans who are currently receiving care at the Medical Center and who are either long term users of SCS for the treatment of their chronic pain or being evaluated for use of SCS to treat their pain.

Official Title

Brain Connectivity Changes With Spinal Cord Stimulation Treatment of Chronic Pain: A Resting State NIRS/EEG Study

Quick Facts

Study Start:2023-07-01
Study Completion:2025-07-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05811312

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * 18 years of age and a US veteran
  2. * Diagnosis of chronic neuropathic pain.
  3. * Current patient at Cleveland VA Medical Center receiving care via Pain Medicine Center.
  4. * Current user of tonic parasthesia-based SCS (pain relief 50% according to NPRS) or undergoing trial SCS period as part of clinical care.
  5. * Able to provide informed consent.
  6. * Medically and psychologically stable.
  1. * Metal in the skull or deformity of the skull
  2. * Pregnancy or pregnancy planning during the study period.
  3. * Unable to provide informed consent.

Contacts and Locations

Study Contact

Cheryl Dudek
CONTACT
(216) 679-3800
cheryl.dudek@va.gov
Holly B Henry
CONTACT
(216) 791-3800
holly.henry@va.gov

Principal Investigator

Svetlana Pundik, MD
PRINCIPAL_INVESTIGATOR
Louis Stokes VA Medical Center, Cleveland, OH

Study Locations (Sites)

Louis Stokes VA Medical Center, Cleveland, OH
Cleveland, Ohio, 44106-1702
United States

Collaborators and Investigators

Sponsor: VA Office of Research and Development

  • Svetlana Pundik, MD, PRINCIPAL_INVESTIGATOR, Louis Stokes VA Medical Center, Cleveland, OH

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-07-01
Study Completion Date2025-07-01

Study Record Updates

Study Start Date2023-07-01
Study Completion Date2025-07-01

Terms related to this study

Keywords Provided by Researchers

  • chronic pain
  • neuropathic pain
  • spinal cord stimulation
  • fNIRS
  • electroencephalography

Additional Relevant MeSH Terms

  • Neuropathic Pain