Topical Treatment for TMJ Arthralgia

Description

The goal of this clinical trial is to evaluate the efficacy of topical 2.5% hydrocortisone in TMJ arthralgia. The main questions it aims to answer are: * How does pain reduction compare? * How does improvement in jaw function limitation compare? * How do side effects compare? Participants will * On day 1 be examined and report their pain level and jaw function limitation * On days 1-21, apply their cream four times a day * On day 21, report their pain level, jaw function limitation, compliance with instructions, and side effects. Researchers will compare topical 2.5% hydrocortisone and topical 1% diclofenac to see if efficacy and side effects differ.

Conditions

TMJ Pain

Study Overview

Study Details

Study overview

The goal of this clinical trial is to evaluate the efficacy of topical 2.5% hydrocortisone in TMJ arthralgia. The main questions it aims to answer are: * How does pain reduction compare? * How does improvement in jaw function limitation compare? * How do side effects compare? Participants will * On day 1 be examined and report their pain level and jaw function limitation * On days 1-21, apply their cream four times a day * On day 21, report their pain level, jaw function limitation, compliance with instructions, and side effects. Researchers will compare topical 2.5% hydrocortisone and topical 1% diclofenac to see if efficacy and side effects differ.

Comparison of Topical 1% Diclofenac and Topical 2.5% Hydrocortisone for TMJ Arthralgia

Topical Treatment for TMJ Arthralgia

Condition
TMJ Pain
Intervention / Treatment

-

Contacts and Locations

San Francisco

Arthur A. Dugoni School of Dentistry, University of the Pacific, San Francisco, California, United States, 94103

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Arthralgia of at least 1 TMJ for at least 3 days
  • * Systemic pain condition
  • * Past adverse reaction to steroid
  • * Currently taking steroid
  • * Taken steroid in the past ___ months
  • * Muscle relaxants (may start after study is complete)
  • * New night guard during study, or within 1 month of start of study (may start after study is complete)

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of the Pacific,

Study Record Dates

2025-04