Acceptability and Efficacy of Pain Reprocessing Therapy in Racially/ Ethnically Diverse Adults With Chronic Back Pain

Description

The goal of this clinical trial is to learn which treatment works better for adults with chronic pain. This study is comparing three treatments: Pain Reprocessing Therapy (PRT), Cognitive Behavioral Therapy (CBT), and usual care (whatever a person is already doing to cope with their pain). The study's main questions are: * Does PRT work well for adults with chronic pain? * Which treatment works better for lowering pain: PRT, CBT, or usual care? This study will compare PRT, CBT, and usual care to see which is most helpful for lowering pain and helping with other problems that people with chronic pain can have.

Conditions

Pain, Chronic, Back Pain

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Study Overview

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Study Details

Study overview

The goal of this clinical trial is to learn which treatment works better for adults with chronic pain. This study is comparing three treatments: Pain Reprocessing Therapy (PRT), Cognitive Behavioral Therapy (CBT), and usual care (whatever a person is already doing to cope with their pain). The study's main questions are: * Does PRT work well for adults with chronic pain? * Which treatment works better for lowering pain: PRT, CBT, or usual care? This study will compare PRT, CBT, and usual care to see which is most helpful for lowering pain and helping with other problems that people with chronic pain can have.

Feasibility and Acceptability of Pain Reprocessing Therapy in Racially/ Ethnically Diverse Adults With Chronic Back Pain

Acceptability and Efficacy of Pain Reprocessing Therapy in Racially/ Ethnically Diverse Adults With Chronic Back Pain

Condition
Pain, Chronic
Intervention / Treatment

-

Contacts and Locations

Aurora

University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States, 80045

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Last-week average back pain of at least 4 of 10 at the two pretreatment timepoints (online pre-screening and informed consent session)
  • * Back pain that is an ongoing problem for at least half the days of the last 6 months
  • * Back pain that is worse than leg pain.
  • * Current litigation or compensation associated with pain or plans to apply for compensation or engage in litigation in the next 6 months
  • * Active suicidal ideation with intent, recent history of suicide attempt, or recent history of suicide attempts or self-harm behaviors within the past 5 years (including non-suicidal self-harm)
  • * Recent history of inpatient psychiatric hospitalization within the past 5 years
  • * Active, current psychosis or mania
  • * Active, current substance abuse, or problems with substance abuse within the past 2 years
  • * Instability in living conditions or major interfering life events:
  • * Major surgery or other major medical event planned in coming six months
  • * Unsure whether will reliably have suitable conditions for telehealth appointments over the next two months, including a computer or tablet, reliable fast internet, and a quiet comfortable room that is reliably available.
  • * Major, interfering changes in employment or housing anticipated over the next six months
  • * Failure to complete at least 85% (6 of 7) of EMA surveys in the first week of the study (post-consent, pre-randomization)
  • * Leg pain worse than back pain
  • * Back surgery within the last 2 years
  • * Difficulty controlling bladder function (to screen out cauda equina syndrome)
  • * Serious medical illness (e.g., current, or recent cancer diagnosis, severe cardiovascular disease)
  • * Recent large unexplained, unintended weight loss (20lbs or more)
  • * Recent vertebral fracture/ known spinal fractures or tumors
  • * Known sensory/motor abnormalities in the trunk or legs.
  • * Self-reported diagnosis of a specific inflammatory disorder: rheumatoid arthritis, polymyalgia rheumatica, scleroderma, Lupus, or polymyositis

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Colorado, Denver,

Jonathan K. Ashar, Ph.D., PRINCIPAL_INVESTIGATOR, University of Colorado, Denver

Study Record Dates

2025-07