Measuring Acute Drug Demand in Humans

Description

This research is being done to evaluate whether suvorexant may reduce the use of, subjective liking, and demand for various drugs.

Conditions

Opioid Use Disorder, Opioid Dependence

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Study Overview

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Study Details

Study overview

This research is being done to evaluate whether suvorexant may reduce the use of, subjective liking, and demand for various drugs.

Measuring Acute Drug Demand in Humans

Measuring Acute Drug Demand in Humans

Condition
Opioid Use Disorder
Intervention / Treatment

-

Contacts and Locations

Baltimore

Behavioral Pharmacology Research Unit, Baltimore, Maryland, United States, 21224

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Age between 18 and 65 years old
  • * Meets Diagnostic and Statistical Manual-5 criteria for Opioid Use Disorder (OUD) (moderate or severe)
  • * Lifetime substance use history criterion \[blinded\]
  • * Medically cleared to take suvorexant and blinded study medications
  • * Be in good general health based on a physical examination, medical history, vital signs, and screening urine and blood tests
  • * Pregnant or breast feeding
  • * Seeking opioid use treatment
  • * Significant mental health or physical disorder that is expected to interfere with study participation as assessed by the study physicians or medical staff
  • * Known contraindications or allergies to suvorexant and/or the blinded study medications

Ages Eligible for Study

18 Years to 65 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Johns Hopkins University,

Justin Strickland, PhD, PRINCIPAL_INVESTIGATOR, Johns Hopkins University

Study Record Dates

2027-10-31