Total Intravenous Anesthesia (TIVA)/Sevoflurane Initiated Intravenous Anesthesia (SIIVA) in Pediatric Patients

Description

Because Propofol is the primary "anesthetic agent," and inhalational agents remain in trace quantities at the end of the procedure Sevoflurane initiated intravenous anesthesia (SIIVA) or not present at all Total intravenous anesthesia (TIVA) it is likely that different criteria may be predictive of extubation success in these patients compared to inhalational anesthesia.

Conditions

Extubation

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Study Overview

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Study Details

Study overview

Because Propofol is the primary "anesthetic agent," and inhalational agents remain in trace quantities at the end of the procedure Sevoflurane initiated intravenous anesthesia (SIIVA) or not present at all Total intravenous anesthesia (TIVA) it is likely that different criteria may be predictive of extubation success in these patients compared to inhalational anesthesia.

A Prospective Observational Study Evaluating Extubation Criteria in Children Less 10 Years of Age and Younger Undergoing Intravenous Anesthesia

Total Intravenous Anesthesia (TIVA)/Sevoflurane Initiated Intravenous Anesthesia (SIIVA) in Pediatric Patients

Condition
Extubation
Intervention / Treatment

-

Contacts and Locations

Winston-Salem

Atrium Health Wake Forest Baptist, Winston-Salem, North Carolina, United States, 27157

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Pediatric patients \<10 years of age
  • * Undergoing elective or emergency surgery with planned airway instrumentation with an endotracheal tube (ETT)
  • * Patients having general anesthesia with a planned SIIVA or TIVA technique
  • * Patients with an end tidal agent concentration of Sevoflurane\<0.1% at the time of emergence and extubation
  • * following sevoflurane induction to place IV
  • * History of home oxygen use or ventilator dependence
  • * Patients with cyanotic congenital heart disease
  • * Patients undergoing anesthesia for imaging procedures alone
  • * Patients intended to be managed with supraglottic airway
  • * Patients having an anesthesia time \< 30 minutes
  • * Monitored Anesthesia Care (not general anesthesia)
  • * Patients with contraindication to receiving Propofol (i.e. mitochondrial myopathy)

Ages Eligible for Study

to 9 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Wake Forest University Health Sciences,

Thomas "Wes" Templeton, MD, PRINCIPAL_INVESTIGATOR, Wake Forest University Health Sciences

Study Record Dates

2028-03