Treatment of Orthostatic Hypotension in SCI

Description

The purpose of this study is to identify the effects of non-pharmacological and pharmacological anti-hypotensive treatment interventions on orthostatic hemodynamic responses, symptoms of autonomic dysreflexia and orthostatic hypotension, and levels of fatigue and comfort in hypotensive individuals with SCI.

Conditions

Hypotension

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Study Overview

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Study Details

Study overview

The purpose of this study is to identify the effects of non-pharmacological and pharmacological anti-hypotensive treatment interventions on orthostatic hemodynamic responses, symptoms of autonomic dysreflexia and orthostatic hypotension, and levels of fatigue and comfort in hypotensive individuals with SCI.

Treatment of Orthostatic Hypotension in Individuals With Spinal Cord Injury

Treatment of Orthostatic Hypotension in SCI

Condition
Hypotension
Intervention / Treatment

-

Contacts and Locations

West Orange

Kessler Foundation, West Orange, New Jersey, United States, 07052

Bronx

James J Peters VA Medical Center, Bronx, New York, United States, 10468

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * traumatic spinal cord injury
  • * at least 12 months post injury
  • * injury level of C1-T6
  • * AIS A, B or C
  • * non-ambulatory
  • * non-ventilator
  • * Active psychiatric disorder
  • * Stroke or cerebrovascular disease
  • * Alzheimer's Disease or dementia
  • * Unmanaged cardiac arrhythmias
  • * Concurrent systemic, hepatic, or renal disease
  • * Suspected or diagnosed malignancy
  • * Neurological disease other than SCI
  • * Self-reported history of three or more symptomatic episodes of AD per day

Ages Eligible for Study

18 Years to 60 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

James J. Peters Veterans Affairs Medical Center,

Study Record Dates

2026-06-30