NSAID Use After Robotic Partial Nephrectomy

Description

The purpose of this study is to see how effective non-steroidal anti-inflammatory drugs (NSAIDs) are at controlling pain without side effects in participants after robotic-assisted partial nephrectomy.

Conditions

Kidney Cancer, Renal Cancer, Renal Neoplasm

Talk to us

Study Overview

On this page

Study Details

Study overview

The purpose of this study is to see how effective non-steroidal anti-inflammatory drugs (NSAIDs) are at controlling pain without side effects in participants after robotic-assisted partial nephrectomy.

NSAID Use After Robotic Partial Nephrectomy (No-PAIN): a Randomized, Controlled Trial

NSAID Use After Robotic Partial Nephrectomy

Condition
Kidney Cancer
Intervention / Treatment

-

Contacts and Locations

Miami

University of Miami, Miami, Florida, United States, 33136

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Patients undergoing uncomplicated robotic assisted laparoscopic partial nephrectomy for renal mass at the University of Miami Hospital and Network Sites (Deerfield Beach, Plantation, Lennar (Coral Gables), and Kendal).
  • * Age 18-99.
  • * Ability to understand and the willingness to sign a written informed consent document.
  • * Allergy to NSAIDs
  • * Myocardial infarction or unstable angina within 12 months.
  • * Any history of coronary artery bypass graft surgery.
  • * History or active peptic ulcer disease, gastrointestinal (GI) bleeding, GI perforation. History of bleeding disorder. Glomerular filtration rate (GFR) \< 60 mL/min/1.73m2 (Modification of Diet in Renal Disease (MDRD) equation).
  • * Taking any anti-platelet or anti-coagulation medications concurrently (e.g. warfarin, aspirin, clopidogrel, rivaroxaban etc.)
  • * Chronic opioid use (use within 12 weeks) or history of opioid use disorder.
  • * Solitary kidney.
  • * Pregnancy.
  • * Inability to give informed consent or unable to meet requirement of the study for any reason.

Ages Eligible for Study

18 Years to 99 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Miami,

Mark L Gonzalgo, MD, PhD, PRINCIPAL_INVESTIGATOR, University of Miami

Study Record Dates

2025-09-30