Reversal of Battle-Related Aging (ROBRA) in a Special Operations Forces Cohort

Description

The purpose of this study is to examine measures of GrimAge clock in SOF members undergoing treatment for PTSD/TBI using CSB.

Conditions

Post-Traumatic Stress Disorder, Traumatic Brain Injury

Study Overview

Study Details

Study overview

The purpose of this study is to examine measures of GrimAge clock in SOF members undergoing treatment for PTSD/TBI using CSB.

Reversal of Battle-Related Aging (ROBRA) in a Special Operations Forces Cohort

Reversal of Battle-Related Aging (ROBRA) in a Special Operations Forces Cohort

Condition
Post-Traumatic Stress Disorder
Intervention / Treatment

-

Contacts and Locations

Westmont

Stella Center, Westmont, Illinois, United States, 60656

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Recruited from SOF with an active duty history of at least 5 years.
  • * Subjects may be in active duty or retired, male and female, between the ages of 40 and 60 years old.
  • * The participants must have a confirmed diagnosis of PTSD, identified by Posttraumatic Stress Disorder Checklist for DSM-5 (PCL-5) scores higher than 40.
  • * The participants must have been on a stable pharmacological or psychotherapeutic therapy for at least three months (if applicable), and continue this treatment throughout the duration of the study.
  • * They must be able and willing to consent for the study. Individuals who are able to become pregnant must adhere to a medically accepted method of contraception (eg. hormonal birth control, barrier birth control, intrauterine device, abstinence).
  • * Existing Horner syndrome;
  • * Allergy to local anesthetics or contrast;
  • * Previous history of stellate ganglion block with psychosis;
  • * Admission to in-patient psychiatric facility within last 3 months;
  • * History of moderate of severe TBI;
  • * Currently pregnant or breastfeeding;
  • * Current substance use disorder, or test positive for 1 or more illegal or controlled drugs on the initial urine drug screen, such as cocaine, marijuana, amphetamines, opioids, benzodiazepines, amongst others;
  • * Previous behavioral health diagnoses (bipolar I, psychosis, etc);
  • * Currently undergoing exposure therapy.

Ages Eligible for Study

40 Years to 60 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Stella Center,

Eugene Lipov, MD, PRINCIPAL_INVESTIGATOR, Stella Center

Study Record Dates

2024-04-05